Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202416312
Abstract: Many adults become vitamin D deficient or insufficient during winter at northerly latitudes when cutaneous vitamin D synthesis does not occur. Vitamin D accumulates in adipose tissue and people with overweight or obesity are more… read more here.
Keywords: weight loss; vitamin; without weight; randomized controlled ... See more keywords
Use of artificial intelligence as a didactic tool to improve ejection fraction assessment in the emergency department: A randomized controlled pilot study
Sign Up to like & getrecommendations! Published in 2022 at "AEM Education and Training"
DOI: 10.1002/aet2.10738
Abstract: Incorporating artificial intelligence (AI) into echocardiography operated by clinicians working in the emergency department to accurately assess left‐ventricular ejection fraction (LVEF) may lead to better diagnostic decisions. This randomized controlled pilot study aimed to evaluate… read more here.
Keywords: controlled pilot; randomized controlled; emergency department; artificial intelligence ... See more keywords
Single‐dose versus low‐dose rituximab in corticosteroid‐resistant or relapsed ITP: A multicenter, randomized, controlled study
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26473
Abstract: Primary immune thrombocytopenia (ITP) is an autoimmune bleeding disorder, in which rituximab (RTX) induces the best long‐term effect among recommended second‐line treatments. Nevertheless, the optimal regimen of RTX remains unclear. We herein conducted a prospective,… read more here.
Keywords: relapsed itp; resistant relapsed; low dose; corticosteroid resistant ... See more keywords
Multicrossover Randomized Controlled Trial Designs in Alzheimer Disease
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DOI: 10.1002/ana.25280
Abstract: Conventional parallel group randomized controlled clinical trials (RCT) in Alzheimer's disease (AD) are too large, long, expensive and insensitive to clinical change to meet the urgent need for an effective treatment. While providing good evidence… read more here.
Keywords: alzheimer disease; parallel group; randomized controlled; crossover ... See more keywords
Adjunctive Thrombolytics After Successful Endovascular Reperfusion: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Neurology"
DOI: 10.1002/ana.70021
Abstract: The efficacy and safety of intra‐arterial thrombolysis (IAT) as an adjunct to endovascular thrombectomy (EVT) in large vessel occlusion strokes (LVOS) remain uncertain, with recent randomized controlled trials (RCTs) yielding conflicting results. This meta‐analysis aimed… read more here.
Keywords: meta analysis; controlled trials; adjunctive thrombolytics; randomized controlled ... See more keywords
A randomized controlled study on medical students learning anatomy through hands‐on ultrasound
Sign Up to like & getrecommendations! Published in 2025 at "Anatomical Sciences Education"
DOI: 10.1002/ase.70078
Abstract: Anatomy education in the undergraduate medical curriculum faces many competing interests, including the increasing demand for ultrasound learning. Instead of being treated as a separate subject, ultrasound can offer a unique lens to visualize anatomy… read more here.
Keywords: hands ultrasound; group; medical students; session ... See more keywords
Parent Outcomes from a Randomized Controlled Trial Investigating a Modular Behavioral Intervention for Young Autistic Children
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DOI: 10.1002/aur.70013
Abstract: We assessed parent stress and competence outcomes from participation in a randomized controlled trial of a modular behavioral intervention (Modular Approach for Young Autistic Children; MAYAC) compared to a treatment‐as‐usual comprehensive behavioral intervention (CBI). Throughout… read more here.
Keywords: trial; behavioral intervention; competence; randomized controlled ... See more keywords
Clinical research associates experience with missing patient reported outcomes data in cancer randomized controlled trials
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3826
Abstract: Missing patient reported outcomes data threaten the validity of PRO‐specific findings and conclusions from randomized controlled trials by introducing bias due to data missing not at random. Clinical Research Associates are a largely unexplored source… read more here.
Keywords: reported outcomes; research; randomized controlled; missing patient ... See more keywords
Health‐related quality of life in stage III‐IV melanoma treated with targeted therapy or immunotherapy: A systematic review on the adequacy of reporting and clinical issues in phase III randomized controlled trials
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5183
Abstract: Cutaneous melanoma represents around over 90% of all melanoma. With more effective treatments able to extend patients' survival, health‐related quality of life (HRQOL) is increasingly becoming an important endpoint in cancer clinical trials. They are… read more here.
Keywords: iii randomized; randomized controlled; controlled trials; hrqol ... See more keywords
Patent foramen ovale (PFO) closure versus medical therapy for prevention of recurrent stroke in patients with prior cryptogenic stroke: A systematic review and meta‐analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.27615
Abstract: We performed a systematic review and meta‐analysis of randomized controlled trials to assess the effect of closure of a patent foramen ovale (PFO) compared with medical therapy for the prevention of stroke in patients with… read more here.
Keywords: randomized controlled; review meta; systematic review; analysis randomized ... See more keywords
Three versus 12‐month dual antiplatelet therapy duration in patients with acute coronary syndrome undergoing percutaneous coronary intervention: A meta‐analysis of randomized controlled trials
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DOI: 10.1002/ccd.30467
Abstract: The American Heart Association/American College of Cardiology guidelines on dual antiplatelet therapy (DAPT) recommend at least 12 months of a P2Y12 inhibitor and low dose aspirin in patients with an acute coronary syndrome (ACS) treated… read more here.
Keywords: coronary syndrome; randomized controlled; acute coronary; antiplatelet therapy ... See more keywords