Use of artificial intelligence as a didactic tool to improve ejection fraction assessment in the emergency department: A randomized controlled pilot study
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DOI: 10.1002/aet2.10738
Abstract: Incorporating artificial intelligence (AI) into echocardiography operated by clinicians working in the emergency department to accurately assess left‐ventricular ejection fraction (LVEF) may lead to better diagnostic decisions. This randomized controlled pilot study aimed to evaluate… read more here.
Keywords: controlled pilot; randomized controlled; emergency department; artificial intelligence ... See more keywords
Single‐dose versus low‐dose rituximab in corticosteroid‐resistant or relapsed ITP: A multicenter, randomized, controlled study
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26473
Abstract: Primary immune thrombocytopenia (ITP) is an autoimmune bleeding disorder, in which rituximab (RTX) induces the best long‐term effect among recommended second‐line treatments. Nevertheless, the optimal regimen of RTX remains unclear. We herein conducted a prospective,… read more here.
Keywords: relapsed itp; resistant relapsed; low dose; corticosteroid resistant ... See more keywords
Multicrossover Randomized Controlled Trial Designs in Alzheimer Disease
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DOI: 10.1002/ana.25280
Abstract: Conventional parallel group randomized controlled clinical trials (RCT) in Alzheimer's disease (AD) are too large, long, expensive and insensitive to clinical change to meet the urgent need for an effective treatment. While providing good evidence… read more here.
Keywords: alzheimer disease; parallel group; randomized controlled; crossover ... See more keywords
Clinical research associates experience with missing patient reported outcomes data in cancer randomized controlled trials
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DOI: 10.1002/cam4.3826
Abstract: Missing patient reported outcomes data threaten the validity of PRO‐specific findings and conclusions from randomized controlled trials by introducing bias due to data missing not at random. Clinical Research Associates are a largely unexplored source… read more here.
Keywords: reported outcomes; research; randomized controlled; missing patient ... See more keywords
Health‐related quality of life in stage III‐IV melanoma treated with targeted therapy or immunotherapy: A systematic review on the adequacy of reporting and clinical issues in phase III randomized controlled trials
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5183
Abstract: Cutaneous melanoma represents around over 90% of all melanoma. With more effective treatments able to extend patients' survival, health‐related quality of life (HRQOL) is increasingly becoming an important endpoint in cancer clinical trials. They are… read more here.
Keywords: iii randomized; randomized controlled; controlled trials; hrqol ... See more keywords
Patent foramen ovale (PFO) closure versus medical therapy for prevention of recurrent stroke in patients with prior cryptogenic stroke: A systematic review and meta‐analysis of randomized controlled trials
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DOI: 10.1002/ccd.27615
Abstract: We performed a systematic review and meta‐analysis of randomized controlled trials to assess the effect of closure of a patent foramen ovale (PFO) compared with medical therapy for the prevention of stroke in patients with… read more here.
Keywords: randomized controlled; review meta; systematic review; analysis randomized ... See more keywords
Three versus 12‐month dual antiplatelet therapy duration in patients with acute coronary syndrome undergoing percutaneous coronary intervention: A meta‐analysis of randomized controlled trials
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DOI: 10.1002/ccd.30467
Abstract: The American Heart Association/American College of Cardiology guidelines on dual antiplatelet therapy (DAPT) recommend at least 12 months of a P2Y12 inhibitor and low dose aspirin in patients with an acute coronary syndrome (ACS) treated… read more here.
Keywords: coronary syndrome; randomized controlled; acute coronary; antiplatelet therapy ... See more keywords
Dose‐dependent effect of aerobic exercise on inflammatory biomarkers in a randomized controlled trial of women at high risk of breast cancer
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DOI: 10.1002/cncr.32530
Abstract: Increased levels of inflammation are associated with many diseases, including cancer. Physical activity can lower breast cancer risk as well as levels of inflammation. The Women In Steady Exercise Research (WISER) Sister trial was a… read more here.
Keywords: risk; trial; randomized controlled; breast cancer ... See more keywords
Cancer health self-efficacy improvement in a randomized controlled trial.
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DOI: 10.1002/cncr.33947
Abstract: BACKGROUND eHealth interventions can help cancer survivors self-manage their health outside the clinic. Little is known about how best to engage and assist survivors across the age and cancer treatment spectra. METHODS The American Cancer… read more here.
Keywords: randomized controlled; self efficacy; controlled trial; cancer ... See more keywords
Digital stress management in cancer: Testing StressProffen in a 12‐month randomized controlled trial
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DOI: 10.1002/cncr.34046
Abstract: Cognitive‐behavioral stress management interventions are associated with improved psychological well‐being for cancer survivors. The availability of, access to, and outreach of these in‐person interventions are limited, however. The current study, therefore, evaluated the efficacy of… read more here.
Keywords: cancer; stress management; controlled trial; month randomized ... See more keywords
Randomized Controlled Trials Versus Real World Evidence: Neither Magic Nor Myth
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DOI: 10.1002/cpt.2083
Abstract: Compared with drugs from the blockbuster era, recently authorized drugs and those expected in the future present a heterogenous mix of chemicals, biologicals, and cell and gene therapies, a sizable fraction being for rare diseases,… read more here.
Keywords: real world; world evidence; randomized controlled; evidence ... See more keywords