Immunomodulating dose of levamisole stimulates innate immune response and prevents intestinal damage in porcine rotavirus diarrhea: a restricted-randomized, single-blinded, and placebo-controlled clinical trial
Sign Up to like & getrecommendations! Published in 2019 at "Tropical Animal Health and Production"
DOI: 10.1007/s11250-019-01833-1
Abstract: A restricted-randomized, single-blinded, placebo-controlled clinical trial was conducted to examine whether immunomodulating dose of levamisole (LMS) can stimulate certain antiviral immune markers by measuring the concentrations of interferon-γ (IFN-γ), nitric oxide (NOx), and total immunoglobulin… read more here.
Keywords: randomized single; trial; response; immunomodulating dose ... See more keywords
Pharmacokinetics and tolerability of oral dosage forms of huperzine a in healthy Chinese male volunteers: a randomized, single dose, three-period, six-sequence crossover study
Sign Up to like & getrecommendations! Published in 2017 at "Current Medical Science"
DOI: 10.1007/s11596-017-1807-8
Abstract: SummaryHuperzine A is a potent, reversible, and blood-brain barrier permeable acetylcholinesterase inhibitor. The aim of this study was to compare the pharmacokinetics, tolerability, and bioavailability of two formulations with the established reference formulation of huperzine… read more here.
Keywords: randomized single; healthy chinese; chinese male; pharmacokinetics tolerability ... See more keywords
A randomized single and multiple ascending dose study in healthy volunteers of LTI‐291, a centrally penetrant glucocerebrosidase activator
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.14772
Abstract: A mutation in the GBA1 gene is the most common genetic risk factor for developing Parkinson's disease. GBA1 encodes the lysosomal enzyme glucosylceramidase beta (glucocerebrosidase, GCase) and mutations decrease enzyme activity. LTI‐291 is an allosteric… read more here.
Keywords: randomized single; glucocerebrosidase; single multiple; lti 291 ... See more keywords
A randomized, single-dose, crossover study of the effects of ulotaront on electrocardiogram intervals in subjects with schizophrenia.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and translational science"
DOI: 10.1111/cts.13512
Abstract: This study (NCT04369391) evaluated the effects of ulotaront (SEP-363856), a novel trace amine-associated receptor 1 (TAAR1) agonist in development for schizophrenia, on electrocardiogram parameters. Study design was a randomized, single-dose, 3-period crossover (ulotaront 150 mg,… read more here.
Keywords: single dose; crossover; effects ulotaront; subjects schizophrenia ... See more keywords
Transformative learning experience among nursing students with patients acting as teachers: Mixed methods, non‐randomized, single‐arm study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Advanced Nursing"
DOI: 10.1111/jan.15364
Abstract: Abstract Aim To examine the effects of expert HIV patients acting as teachers to Spanish nursing students both on their HIV‐related knowledge, attitudes and practices and on their approach to the care model as well… read more here.
Keywords: non randomized; patients acting; learning experience; acting teachers ... See more keywords
A randomized, single‐blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12339
Abstract: A topical healing system containing a combination of active ingredients including a tripeptide and hexapeptide (TriHex Technology™) has been found to stimulate neoelastogenesis and neocollagenesis. read more here.
Keywords: randomized single; trial tripeptide; hexapeptide; single blinded ... See more keywords
A randomized, single-blind, prospective trial of auricular 'battlefield' acupuncture for the reduction of postoperative tonsillectomy pain in adults.
Sign Up to like & getrecommendations! Published in 2018 at "Pain management"
DOI: 10.2217/pmt-2018-0007
Abstract: AIM The purpose of this randomized, single-blind trial was to evaluate the efficacy of battlefield acupuncture in reducing postoperative pain and opioid consumption after adult tonsillectomy. METHODS Adult participants undergoing a tonsillectomy were randomized to… read more here.
Keywords: battlefield acupuncture; randomized single; acupuncture; tonsillectomy ... See more keywords
A randomized single-blind controlled trial of a prototype digital polytherapeutic for tinnitus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.958730
Abstract: Objective This randomized single-blind controlled trial tested the hypothesis that a prototype digital therapeutic developed to provide goal-based counseling with personalized passive and active game-based sound therapy would provide superior tinnitus outcomes, and similar usability,… read more here.
Keywords: single blind; trial; tinnitus; group ... See more keywords
The MOTIV-HEART Study: A Prospective, Randomized, Single-Blind Pilot Study of Brief Strategic Therapy and Motivational Interviewing among Cardiac Rehabilitation Patients
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2017.00083
Abstract: Background: Psychological distress, biomedical parameters, and unhealthy lifestyles contribute to a poorer prognosis for cardiac disease. Public health's challenge is to motivate patients to utilize self-care. Objective: This prospective, randomized, single-blind pilot study aimed at… read more here.
Keywords: randomized single; prospective randomized; pilot study; study ... See more keywords
Amino Acid Plasma Profiles from a Prolonged-Release Protein Substitute for Phenylketonuria: A Randomized, Single-Dose, Four-Way Crossover Trial in Healthy Volunteers
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12061653
Abstract: Several disorders of amino acid (AA) metabolism are treated with a protein-restricted diet supplemented with specific AA mixtures. Delivery kinetics impacts AA absorption and plasma concentration profiles. We assessed plasma profiles after ingestion of an… read more here.
Keywords: randomized single; plasma profiles; trial; plasma ... See more keywords
A randomized, single-blinded cross-over trial of ischemic preconditioning in Raynaud's phenomenon
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Scleroderma and Related Disorders"
DOI: 10.5301/jsrd.5000253
Abstract: Introduction Ischemic preconditioning (IPC) is protective against future ischemia, with brief cycles of ischemia and reperfusion leading to the release of circulating endogenous compounds from ischemic cells. IPC may increase vasodilatory substances and improve Raynaud's… read more here.
Keywords: randomized single; ipc; week; single blinded ... See more keywords