Safety of Anticoagulation Interruption in Patients Undergoing Surgery or Invasive Procedures: A Systematic Review and Meta-analyses of Randomized Controlled Trials and Non-randomized Studies
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Surgery"
DOI: 10.1007/s00268-017-4072-x
Abstract: BackgroundThe safety of anticoagulation interruption in patients requiring surgical or invasive procedures remains unclear. We thus performed a systematic review and meta-analyses of randomized controlled trials (RCTs) and non-randomized studies (NRS).MethodsMEDLINE, Embase and Central databases… read more here.
Keywords: anticoagulation; safety; randomized studies; anticoagulation interruption ... See more keywords
When are randomized trials unnecessary? A signal detection theory approach to approving new treatments based on non-randomized studies.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of evaluation in clinical practice"
DOI: 10.1111/jep.13497
Abstract: RATIONALE, AIMS AND OBJECTIVES New therapies are increasingly approved by regulatory agencies such as the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) based on testing in non-randomized clinical trials. These treatments… read more here.
Keywords: based non; randomized studies; signal detection; detection theory ... See more keywords
Study filters for non-randomized studies of interventions consistently lacked sensitivity upon external validation
Sign Up to like & getrecommendations! Published in 2018 at "BMC Medical Research Methodology"
DOI: 10.1186/s12874-018-0625-4
Abstract: BackgroundLittle evidence is available on searches for non-randomized studies (NRS) in bibliographic databases within the framework of systematic reviews. For instance, it is currently unclear whether, when searching for NRS, effective restriction of the search… read more here.
Keywords: nrs filters; study types; study; randomized studies ... See more keywords
Overall survival analysis of the FOXFIRE prospective randomized studies of first-line selective internal radiotherapy (SIRT) in patients with liver metastases from colorectal cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.3507
Abstract: 3507Background: The FOXFIRE, SIRFLOX and FOXFIRE-Global (FF-SF-FFG) randomized studies evaluated the efficacy of combining first-line chemotherapy for metastatic colorectal cancer (mCRC) with selec... read more here.
Keywords: foxfire; first line; colorectal cancer; randomized studies ... See more keywords
Meta-analyses and approach of the real impact of anorexigenic drugs in the obesity in humans: the last five years of the randomized studies.
Sign Up to like & getrecommendations! Published in 2019 at "Current diabetes reviews"
DOI: 10.2174/1573399815666191113125247
Abstract: INTRODUCTION Obesity shows a multifactorial disease and presents a serious public health problem, with an alarming epidemic character. According to NHANES (National Health and Nutrition Examination Survey) from 2015 to 2016, 39.6% of American adults… read more here.
Keywords: weight loss; five years; anorexigenic drugs; randomized studies ... See more keywords
Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.774251
Abstract: Background In non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the treatment/exposure group and control… read more here.
Keywords: meta analysis; non randomized; outcome; randomized studies ... See more keywords
Fractional Flow Reserve-Guided Coronary Revascularization: Evidence from Randomized and Non-Randomized Studies
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DOI: 10.3390/diagnostics12112659
Abstract: Simple visual estimation of coronary angiography is limited by several factors that can hinder the proper classification of coronary lesions. Fractional flow reserve (FFR) is the most widely used tool to perform a physiological evaluation… read more here.
Keywords: non randomized; randomized non; randomized studies; fractional flow ... See more keywords