Selective Chemical Labeling Strategy for Oligonucleotides Determination: A First Application to Full-Range Profiling of Transfer RNA Modifications.
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DOI: 10.1021/acs.analchem.2c02302
Abstract: To date, the extremely high polarity and poor signal intensity of macromolecular nucleic acids are greatly impeding the progress of mass spectrometry technology in the quality control of nucleic acid drugs and the characterization of… read more here.
Keywords: rna; full range; range profiling; determination ... See more keywords