Postnatal Expression and Possible Function of RANK and RANKL in the Murine Inner Ear.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115837
Abstract: The bone encasing the inner ear, known as the otic capsule, is unique because it remodels little postnatally compared to other bones in the body. Previous studies established that osteoprotegerin (OPG) in the inner ear… read more here.
Keywords: inner ear; expression; rank rankl; function ... See more keywords
RANK-RANKL signaling upregulates Il-10 mRNA expression in mucosal Candida infection in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104285
Abstract: Osteoprotegerin (OPG) prevents binding of receptor activator of nuclear factor-kappa B ligand (RANKL) to RANK. Recent studies have reported that immune cell RANK-RANKL interactions are critical to the infection process. Candida albicans is an opportunistic… read more here.
Keywords: opg; infection; expression; rank rankl ... See more keywords
25-Hydroxycholesterol induces odontoclastic differentiation through RANK-RANKL upregulation and NF-κB activation in odontoblast-like MDPC-23 cells: An in vitro study.
Sign Up to like & getrecommendations! Published in 2022 at "International endodontic journal"
DOI: 10.1111/iej.13878
Abstract: AIM The physiological effects and cellular mechanism of 25-hydroxycholesterol (25-HC), which is an oxysterol synthesized from cholesterol by cholesterol-25-hydroxylase (CH25H) expressed under inflammatory conditions, are still largely unknown during odontoclastogenesis. This study aimed to evaluate… read more here.
Keywords: mdpc; mdpc cells; expression; rank rankl ... See more keywords
A Comparison of Ki67, Syndecan-1 (CD138), and Molecular RANK, RANKL, and OPG Triad Expression in Odontogenic Keratocyts, Unicystic Ameloblastoma, and Dentigerous Cysts
Sign Up to like & getrecommendations! Published in 2018 at "Disease Markers"
DOI: 10.1155/2018/7048531
Abstract: Background and Objective Reduced expression of syndecan-1 (CD138), increased proliferation index, and modifications in the expression of the molecular RANK/RANKL/OPG triad are related to an intensified potential of aggressiveness and invasion of diverse tumors and… read more here.
Keywords: rankl opg; expression; rank rankl; cd138 ... See more keywords
Abstract 2830: Fluoxetine mediate radiosensitivity and inhibit metastasis of osteosarcoma cells via RANK/RANKL signaling
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2830
Abstract: Osteosarcoma (OS) is most common primary malignant bone tumour OS was flagrantly byaffecting pediatric and young adolescents patients with its outrageous metastatic rate and poorprognosis. It was aggressive in local invasion and further metastasis, especially… read more here.
Keywords: metastasis; rank rankl; cells via; fluoxetine ... See more keywords
OPG/RANK/RANKL signaling axis in patients with type I diabetes: Associations with parathormone and vitamin D
Sign Up to like & getrecommendations! Published in 2019 at "Italian Journal of Pediatrics"
DOI: 10.1186/s13052-019-0748-1
Abstract: BackgroundType 1 diabetes (T1D) has been associated with a higher fracture risk due to alterations in bone structure and metabolism. On the other hand, the important role of the RANKL/OPG/RANK signaling axis in bone physiology… read more here.
Keywords: opg rank; signaling axis; rank rankl; rankl ... See more keywords
Modulation of the RANK/RANKL/OPG system and FOXP3+ regulatory T cells in the tumor microenvironment of noninvasive bladder cancer after intravesical oncotherad immunotherapy associated with platelet-rich plasma.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.6_suppl.462
Abstract: 462Background: The activity of the receptor activator of nuclear factor-kβ RANK/RANKL in cancer cells has been correlated with tumor progression and poor prognosis in solid tumors including bladder... read more here.
Keywords: rank rankl; cancer; rank; tumor ... See more keywords
The Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.903657
Abstract: Although their physiology and functions are very different, bones, skeletal and smooth muscles, as well as the heart have the same embryonic origin. Skeletal muscles and bones interact with each other to enable breathing, kinesis,… read more here.
Keywords: opg pathway; skeletal smooth; rank rankl; rankl opg ... See more keywords
Capecitabine inhibits epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells by mediating the RANK/RANKL pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13216
Abstract: Colorectal cancer (CRC) is the third most prevalent malignancy globally. Capecitabine is an important form of chemotherapy for colorectal cancer. The present study aims to investigate the underlying mechanism of action of the drug in… read more here.
Keywords: rank rankl; colorectal cancer; rankl pathway; rank ... See more keywords