The activin receptor is stimulated in the skeleton, vasculature, heart, and kidney during chronic kidney disease.
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DOI: 10.1016/j.kint.2017.06.016
Abstract: We examined activin receptor type IIA (ActRIIA) activation in chronic kidney disease (CKD) by signal analysis and inhibition in mice with Alport syndrome using the ActRIIA ligand trap RAP-011 initiated in 75-day-old Alport mice. At… read more here.
Keywords: disease; ckd; mice; activin receptor ... See more keywords