Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a, and neutrophil migration.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental hematology"
DOI: 10.1016/j.exphem.2017.04.001
Abstract: Podocalyxin (Podxl) is a CD34 orthologue and cell surface sialomucin reported to have roles in renal podocyte diaphragm slit development; vascular cell integrity; and the progression of blood, breast, and prostate cancers. Roles for Podxl… read more here.
Keywords: novel roles; rap1a; stress; podxl ... See more keywords
Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52163-z
Abstract: Age-related macular degeneration (AMD) is a multifactorial chronic disease that requires long term treatment. Gene therapy is being considered as a promising tool to treat AMD. We found that increased activation of Rap1a in the… read more here.
Keywords: rap1a rpe; active rap1a; scaav2 vmd2; rap1a ... See more keywords