Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets
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DOI: 10.1080/09537104.2022.2071855
Abstract: Abstract Platelet activation by adenosine diphosphate (ADP) is mediated through two G-protein-coupled receptors, P2Y1 and P2Y12, which signal through Gq and Gi, respectively. P2Y1 stimulation leads to phospholipase C activation and an increase in cytosolic… read more here.
Keywords: pi3 kinase; p2y12; activation; rap1b activation ... See more keywords