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Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts

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0 Published in 2018 at "GeroScience"

DOI: 10.1007/s11357-018-0030-2

Abstract: Inhibition of mTOR signaling using rapamycin has been shown to increase lifespan and healthspan in multiple model organisms; however, the precise mechanisms for the beneficial effects of rapamycin remain uncertain. We have previously reported that… read more here.

Keywords: rapamycin increases; oxidative metabolism; senescence; increases oxidative ... See more keywords