The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-01014-x
Abstract: The mammalian target of rapamycin (mTOR) is a ubiquitously expressed serine/threonine kinase protein complex (mTORC1 or mTORC2) that orchestrates diverse functions ranging from embryonic development to aging. However, its brain tissue-specific roles remain less explored.… read more here.
Keywords: haloperidol induced; rapamycin mtor; mammalian target; mtor ... See more keywords
The case for the therapeutic use of mechanistic/mammalian target of rapamycin (mTOR) inhibitors in xenotransplantation.
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DOI: 10.1111/xen.12802
Abstract: The mechanistic/mammalian target of rapamycin (mTOR) is one of the systems that are necessary to maintain cell homeostasis, such as survival, proliferation, and differentiation. mTOR inhibitors (mTOR‐Is) are utilized as immunosuppressants and anti‐cancer drugs. In… read more here.
Keywords: target rapamycin; mtor inhibitors; mechanistic mammalian; mammalian target ... See more keywords
Involvement of Mechanistic Target of Rapamycin (mTOR) in Valine Orexigenic Effects in Rainbow Trout
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DOI: 10.1155/2022/7509382
Abstract: This study was aimed at clarifying the importance of a mechanistic target of rapamycin (mTOR) in the central orexigenic effect of valine in fish. For this, rainbow trout (Oncorhynchus mykiss) were intracerebroventricularly (ICV) injected with… read more here.
Keywords: rainbow trout; mechanistic target; valine; mtor ... See more keywords
Mechanistic Target of Rapamycin (mTOR) in the Cancer Setting
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DOI: 10.3390/cancers10060168
Abstract: This special issue on mammalian target of rapamycin (mTOR) explores the importance of mTOR in cell growth control and cancer. Cancer cells often exploit mTOR as a mechanism to enhance their capacity to grow. While… read more here.
Keywords: cancer; rapamycin mtor; mtor; target rapamycin ... See more keywords
Mammalian Target of Rapamycin (mTOR) Signaling at the Crossroad of Muscle Fiber Fate in Sarcopenia
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DOI: 10.3390/ijms232213823
Abstract: The mammalian target of rapamycin (mTOR) is a major regulator of skeletal myocyte viability. The signaling pathways triggered by mTOR vary according to the type of endogenous and exogenous factors (e.g., redox balance, nutrient availability,… read more here.
Keywords: target rapamycin; mtor signaling; mammalian target; sarcopenia ... See more keywords
The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling
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DOI: 10.3390/nu9111176
Abstract: The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that controls a wide spectrum of cellular processes, including cell growth, differentiation, and metabolism. mTOR forms two distinct multiprotein complexes known as mTOR complex 1… read more here.
Keywords: insulin; rapamycin mtor; mammalian target; mtor ... See more keywords
Suppression of Thioacetamide-Induced Hepatic Injury in Rats treatment with Resveratrol: Role of mammalian Target of Rapamycin (mTOR) Cell Signaling
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Morphology"
DOI: 10.4067/s0717-95022020000300558
Abstract: Chronic hepatotoxicity is a debilitating and frequently life-threatening disease resulting in progressive liver failure. The toxic chemical, thioacetamide (TAA) is used to evaluate hepatoprotective agents, and the polyphenolic compound, resveratrol wa proposed as a novel… read more here.
Keywords: resveratrol; rapamycin mtor; mammalian target; mtor ... See more keywords