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Published in 2021 at "Progress in brain research"
DOI: 10.1016/bs.pbr.2021.02.003
Abstract: The brainstem is a neglected brain area in neurodegenerative diseases, including Alzheimer's and Parkinson's disease, frontotemporal lobar degeneration and autonomic dysfunction. In Depression, several observations have been made in relation to changes in one particular…
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Keywords:
raphe nucleus;
area;
relation;
dorsal raphe ... See more keywords
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Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.11.006
Abstract: HIGHLIGHTSMicroinjection of SKF38393, bromocriptine and quinpirole into the DRN reduced REMS.Bromocriptine and quinpirole increased, in addition, wakefulness.The DAergic system plays a role in the regulation of the 5‐HT system. ABSTRACT The effects of the dopamine…
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Keywords:
raphe nucleus;
dorsal raphe;
receptor agonists;
dopamine receptor ... See more keywords
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Published in 2021 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2020.11.016
Abstract: BACKGROUND Estrogen increases dramatically during pregnancy but quickly drops below prepregnancy levels at birth and remains suppressed during the postpartum period. Clinical and rodent work suggests that this postpartum drop in estrogen results in an…
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Keywords:
raphe nucleus;
anxiety;
estrogen withdrawal;
estrogen ... See more keywords
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Published in 2019 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2018.09.015
Abstract: &NA; The central serotonin2B receptor (5‐HT2BR) is a well‐established modulator of dopamine (DA) neuron activity in the rodent brain. Recent studies in rats have shown that the effect of 5‐HT2BR antagonists on accumbal and medial…
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Keywords:
raphe nucleus;
drn;
control;
tonic inhibitory ... See more keywords
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Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118777
Abstract: The dorsal raphe nucleus (DRN) is a brainstem nucleus involved in the pathophysiology of the depression, through its serotoninergic innervation. Furthermore, depressive symptoms in patients are also associated with some memory and sleep complaints. Anatomical…
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Keywords:
orexin;
raphe nucleus;
spatial reference;
reference memory ... See more keywords
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Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.12.034
Abstract: Lactating female mice nurture their pups and attack intruders in their territory. When an intruder invades a dam's territory, she needs to switch her behavior from care to aggression to protect her pups and territory.…
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Keywords:
glutamatergic signals;
raphe nucleus;
nurturing behavior;
aggression ... See more keywords
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Published in 2020 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-020-0616-0
Abstract: The lateral habenula (LHb) processes information about aversive experiences that contributes to the symptoms of stress disorders. Previously, we found that chemogenetic inhibition of rat LHb neurons reduced immobility in the forced swim test, but…
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Keywords:
lhb neurons;
raphe nucleus;
inhibition;
dorsal raphe ... See more keywords
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Published in 2019 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001158
Abstract: The dorsal raphe nucleus (DR) is a crucial source of serotonin (5-HT) neurons involved in the regulation of stress-induced depression. Estrogen receptors have been identified in the DR, yet the role of estrogen in modulating…
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Keywords:
expression;
mgr;
receptor;
estrogen ... See more keywords
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Published in 2020 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001501
Abstract: Serotonin (5-HT) has an important role in the pathophysiology of the mood disorders like major depression and anxiety disorders in central nervous system. On the one hand, dorsal raphe nucleus (DRN) neurons send serotonergic projections…
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Keywords:
potassium;
neurons mice;
drn neurons;
dorsal raphe ... See more keywords
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Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.oa1753
Abstract: Based on results from genetic, neuropharmacological and electrophysiological studies, serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) apparently function predominantly to promote wakefulness and inhibit REM sleep. However, the effects of 5-HT on sleep…
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Keywords:
state;
raphe nucleus;
vigilance state;
neurons dorsal ... See more keywords
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Published in 2021 at "eLife"
DOI: 10.7554/elife.67638
Abstract: Consolation is a common response to the distress of others in humans and some social animals, but the neural mechanisms underlying this behavior are not well characterized. By using socially monogamous mandarin voles, we found…
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Keywords:
cingulate cortex;
dorsal raphe;
sociability;
consolation ... See more keywords