Use of metamodels for rapid discovery of narrow bandgap oxide photocatalysts
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103068
Abstract: Summary New photocatalysts are traditionally identified through trial-and-error methods. Machine learning has shown considerable promise for improving the efficiency of photocatalyst discovery from a large potential pool. Here, we describe a multi-step, target-driven consensus method… read more here.
Keywords: bandgap; discovery narrow; use metamodels; metamodels rapid ... See more keywords
Toolkit for automated and rapid discovery of structural variants.
Sign Up to like & getrecommendations! Published in 2017 at "Methods"
DOI: 10.1016/j.ymeth.2017.05.030
Abstract: Structural variations (SV) are broadly defined as genomic alterations that affect >50bp of DNA, which are shown to have significant effect on evolution and disease. The advent of high throughput sequencing (HTS) technologies and the… read more here.
Keywords: discovery structural; automated rapid; structural variants; toolkit automated ... See more keywords
Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00184
Abstract: Anthrax, a lethal, weaponizable disease caused by Bacillus anthracis, acts through exotoxins that are primary mediators of systemic toxicity and also targets for neutralization by passive immunotherapy. The ease of engineering B. anthracis strains resistant… read more here.
Keywords: anthrax edema; discovery characterization; anthrax; antibody ... See more keywords
Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells
Sign Up to like & getrecommendations! Published in 2024 at "Nature Biotechnology"
DOI: 10.1038/s41587-024-02346-5
Abstract: Monoclonal antibodies are increasingly used to prevent and treat viral infections and are pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and plasmablasts) are an excellent source of high-affinity antibodies with therapeutic potential.… read more here.
Keywords: antibody; antibody secreting; discovery monoclonal; secreting cells ... See more keywords
Symmetry Strategy for Rapid Discovery of Abundant Fractional Quantum Ferroelectrics.
Sign Up to like & getrecommendations! Published in 2025 at "Physical review letters"
DOI: 10.1103/physrevlett.134.016801
Abstract: Traditional ferroelectrics are limited by Neumann's principle, which confines exploration of ferroelectrics within polar point groups. Our recent work [Ji et al., Nat. Commun. 15, 135 (2024)NCAOBW2041-172310.1038/s41467-023-44453-y] proposes the concept of fractional quantum ferroelectricity (FQFE) that… read more here.
Keywords: fractional quantum; rapid discovery; strategy rapid; symmetry strategy ... See more keywords
Erratum: An Integrated Strategy for Rapid Discovery and Identification of Quality Markers in Gardenia Fructus Using an Omics Discrimination-Grey Correlation-Biological Verification Method
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.742055
Abstract: [This corrects the article DOI: 10.3389/fphar.2021.705498.]. read more here.
Keywords: discovery identification; identification quality; erratum integrated; strategy rapid ... See more keywords
Rapid Discovery of Antimicrobial and Antimalarial Agents from Natural Product Fragments
Sign Up to like & getrecommendations! Published in 2024 at "Separations"
DOI: 10.3390/separations11070194
Abstract: Fragment-based drug discovery (FBDD) focuses on small compounds, known as fragments, typically with a molecular weight of less than 300 Da. This study highlights the benefits of employing a pure natural product library for FBDD,… read more here.
Keywords: product fragments; product; natural product; antimicrobial antimalarial ... See more keywords
Catalyzing rapid discovery of gold-precipitating bacterial lineages with university students
Sign Up to like & getrecommendations! Published in 2020 at "PeerJ"
DOI: 10.7717/peerj.8925
Abstract: Intriguing and potentially commercially useful microorganisms are found in our surroundings and new tools allow us to learn about their genetic potential and evolutionary history. Engaging students from different disciplines and courses in the search… read more here.
Keywords: gold precipitating; gold; catalyzing rapid; rapid discovery ... See more keywords