A case–control–family study of idiopathic rapid eye movement sleep behavior disorder
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DOI: 10.1002/ana.25435
Abstract: To determine the familial aggregation of idiopathic rapid eye movement sleep behavior disorder (iRBD), neurodegenerative diseases, and related biomarkers. read more here.
Keywords: idiopathic rapid; behavior disorder; rapid eye; eye movement ... See more keywords
Fine‐Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies
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DOI: 10.1002/ana.25687
Abstract: Rapid eye movement sleep behavior disorder (RBD) is a prodromal synucleinopathy, as >80% will eventually convert to overt synucleinopathy. We performed an in‐depth analysis of the SNCA locus to identify RBD‐specific risk variants. read more here.
Keywords: behavior disorder; rapid eye; eye movement; movement sleep ... See more keywords
Risk Factors for Phenoconversion in Rapid Eye Movement Sleep Behavior Disorder
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DOI: 10.1002/ana.26298
Abstract: This study was undertaken to follow up predictive factors for α‐synuclein–related neurodegenerative diseases in a multicenter cohort of idiopathic/isolated rapid eye movement sleep behavior disorder (iRBD). read more here.
Keywords: rapid eye; movement sleep; behavior disorder; eye movement ... See more keywords
Actigraphy Enables Home Screening of Rapid Eye Movement Behavior Disorder in Parkinson's Disease
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DOI: 10.1002/ana.26517
Abstract: Rapid eye movement sleep behavior disorder (RBD) is a potentially harmful, often overlooked sleep disorder affecting up to 70% of Parkinson's disease patients. Current diagnosis relies on nocturnal video‐polysomnography, which is an expensive and cumbersome… read more here.
Keywords: behavior disorder; parkinson disease; eye movement; rapid eye ... See more keywords
Rapid Eye Movement Sleep, Neurodegeneration, and Amyloid Deposition in Aging
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DOI: 10.1002/ana.26604
Abstract: Rapid eye movement (REM) sleep is markedly altered in Alzheimer's disease (AD), and its reduction in older populations is associated with AD risk. However, little is known about the underlying brain mechanisms. Our objective was… read more here.
Keywords: eye movement; rapid eye; amyloid deposition;
Rapid eye movement sleep patterns of brain activation and deactivation occur within unique functional networks
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DOI: 10.1002/hbm.25102
Abstract: Abstract Rapid eye movement (REM) sleep is a paradoxical state where the individual appears asleep while the electroencephalogram pattern resembles that of wakefulness. Regional differences in brain metabolism have been observed during REM sleep compared… read more here.
Keywords: activation deactivation; rem sleep; rapid eye; activation ... See more keywords
Degeneration of rapid eye movement sleep circuitry underlies rapid eye movement sleep behavior disorder
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DOI: 10.1002/mds.27003
Abstract: During healthy rapid eye movement sleep, skeletal muscles are actively forced into a state of motor paralysis. However, in rapid eye movement sleep behavior disorder—a relatively common neurological disorder—this natural process is lost. A lack… read more here.
Keywords: movement; rapid eye; eye movement; disorder ... See more keywords
The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder
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DOI: 10.1002/mds.27105
Abstract: Increasing evidence connects the gut microbiota and the onset and/or phenotype of Parkinson's disease (PD). Differences in the abundances of specific bacterial taxa have been reported in PD patients. It is, however, unknown whether these… read more here.
Keywords: idiopathic rapid; movement; rapid eye; eye movement ... See more keywords
Full sequencing and haplotype analysis of MAPT in Parkinson's disease and rapid eye movement sleep behavior disorder
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DOI: 10.1002/mds.27385
Abstract: Background: MAPT haplotypes are associated with PD, but their association with rapid eye movement sleep behavior disorder is unclear. read more here.
Keywords: behavior disorder; movement; rapid eye; eye movement ... See more keywords
Subtle gait and balance impairments occur in idiopathic rapid eye movement sleep behavior disorder
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DOI: 10.1002/mds.27780
Abstract: Although motor abnormalities have been flagged as potentially the most sensitive and specific clinical features for predicting the future progression to Parkinson's disease, little work has been done to characterize gait and balance impairments in… read more here.
Keywords: idiopathic rapid; movement; rapid eye; eye movement ... See more keywords
Prodromal Marker Progression in Idiopathic Rapid Eye Movement Sleep Behavior Disorder: Sample Size for Clinical Trials
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DOI: 10.1002/mds.27869
Abstract: To estimate prodromal marker progression in idiopathic rapid eye movement sleep behavior disorder patients with prodromal Parkinson's disease (PD) to calculate sample size for neuroprotective trials. read more here.
Keywords: idiopathic rapid; movement; rapid eye; prodromal marker ... See more keywords