Rapid Generation of Circulating and Mucosal Decoy Human ACE2 using mRNA Nanotherapeutics for the Potential Treatment of SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202556
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can cause lethal pulmonary damage in humans. It contains spike proteins on its envelope that bind to human angiotensin‐converting enzyme 2 (hACE2) expressed on airway cells, enabling entry… read more here.
Keywords: generation circulating; rapid generation; hsace2; treatment ... See more keywords
Rapid Generation of miRNA Inhibitor Leads by Bioinformatics and Efficient High-Throughput Screening Methods.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6563-2_13
Abstract: The discovery of microRNAs (miRNAs) has opened an entire new avenue for drug development. These short (15-22 nucleotides) noncoding RNAs, which function in RNA silencing and posttranscriptional regulation of gene expression, have been shown to… read more here.
Keywords: generation mirna; mir 544; efficient high; rapid generation ... See more keywords
Rapid generation of volatile fatty acids (VFA) through anaerobic acidification of livestock organic waste at low hydraulic residence time (HRT).
Sign Up to like & getrecommendations! Published in 2017 at "Bioresource technology"
DOI: 10.1016/j.biortech.2017.04.005
Abstract: The purpose of this study was to investigate the effect of pre-treatment and F/M (Food to Microorganism) ratios for the rapid generation of volatile fatty acids (VFA) from livestock organic wastes (cattle manure (CM) and… read more here.
Keywords: treatment; fatty acids; volatile fatty; generation volatile ... See more keywords
MolTaut: A Tool for the Rapid Generation of Favorable Tautomer in Aqueous Solution
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c01393
Abstract: Fast and proper treatment of the tautomeric states for drug-like molecules is critical in computer-aided drug discovery since the major tautomer of a molecule determines its pharmacophore features and physical properties. We present MolTaut, a… read more here.
Keywords: tool; tautomer; rapid generation; moltaut tool ... See more keywords
Rapid Generation of Metal-Organic Framework Phase Diagrams by High-Throughput Transmission Electron Microscopy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01095
Abstract: Metal-organic frameworks (MOFs) constructed from Zr6 nodes and tetratopic carboxylate linkers display high structural diversity and complexity in which various crystal topologies can result from identical building units. To determine correlations between MOF topologies and… read more here.
Keywords: rapid generation; microscopy; metal organic; modulator ... See more keywords
Rapid generation of functional engineered 3D human neuronal assemblies: network dynamics evaluated by micro-electrodes arrays
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neural Engineering"
DOI: 10.1088/1741-2552/ac3e02
Abstract: Objective. In this work we adapted a protocol for the fast generation of human neurons to build 3D neuronal networks with controlled structure and cell composition suitable for systematic electrophysiological investigations. Approach. We used biocompatible… read more here.
Keywords: rapid generation; generation functional; neuronal networks; functional engineered ... See more keywords
Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation
Sign Up to like & getrecommendations! Published in 2021 at "National Science Review"
DOI: 10.1093/nsr/nwaa285
Abstract: Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation Feng-Liang Liu1,†, Kaixin Wu2,3,7,8,†, Jiaoyang Sun3,4,6,†, Zilei Duan1,†, Xiongzhi Quan2,3, Junqi Kuang2,3,4, Shilong Chu2,3, Wei Pang2,3, Han Gao2, Ling Xu1, Ying-Chang Li1,… read more here.
Keywords: ace2 humanized; generation ace2; inbred mouse; humanized inbred ... See more keywords
Two schemes for rapid generation of digital video holograms using PC cluster
Sign Up to like & getrecommendations! Published in 2017 at "Optical Engineering"
DOI: 10.1117/1.oe.56.12.123104
Abstract: Abstract. Computer-generated holography (CGH), which is a process of generating digital holograms, is computationally expensive. Recently, several methods/systems of parallelizing the process using graphic processing units (GPUs) have been proposed. Indeed, use of multiple GPUs… read more here.
Keywords: generation digital; system; digital video; generation ... See more keywords
Rapid Generation of Attenuated Infectious Bursal Disease Virus from Dual-Promoter Plasmids by Reduction of Viral Ribonucleoprotein Activity
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Virology"
DOI: 10.1128/jvi.01569-19
Abstract: Immunosuppression in chickens as a result of infectious bursal disease virus (IBDV) infection leads to significant economic losses in the poultry industry worldwide every year. Currently, vaccination is still the best way to prevent the… read more here.
Keywords: dual promoter; rapid generation; ibdv; activity ... See more keywords
Rapid generation of perfect vortex beam without side lobes
Sign Up to like & getrecommendations! Published in 2018 at "Modern Physics Letters B"
DOI: 10.1142/s0217984918502895
Abstract: We have proposed an approach for rapid generation of perfect vortex beam without side lobes through a digital micromirror device (DMD). Employing this method, the amplitude and phase of far field c... read more here.
Keywords: beam without; perfect vortex; vortex beam; generation perfect ... See more keywords
Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0282064
Abstract: Combination nanomedicine is a potent strategy for cancer treatment. Exploiting different mechanisms of action, a novel triple drug delivery system of 5-fluorouracil, curcumin, and piperine co-loaded human serum albumin nanoparticles (5FU-CUR-PIP-HSA-NPs) was developed via the… read more here.
Keywords: tumor; rapid generation; drug; generation homogenous ... See more keywords