A well-tolerated and rapidly acting thiopurine for IBD?
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2018.09.001
Abstract: Thiopurine drugs continue to be a cornerstone of inflammatory bowel disease (IBD) treatment. Thiopurines are economical compared with many newer medical treatments for IBD, other chronic inflammatory diseases and leukaemia, although they are not without… read more here.
Keywords: rapidly acting; thiopurine; tolerated rapidly; ibd ... See more keywords
Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation.
Sign Up to like & getrecommendations! Published in 2021 at "Nature neuroscience"
DOI: 10.1038/s41593-021-00868-8
Abstract: The rapidly acting antidepressants ketamine and scopolamine exert behavioral effects that can last from several days to more than a week in some patients. The molecular mechanisms underlying the maintenance of these antidepressant effects are… read more here.
Keywords: ketamine scopolamine; rapidly acting; acting antidepressants; mecp2 phosphorylation ... See more keywords
N-Acetylcysteine as a novel rapidly acting anti-suicidal agent: A pilot naturalistic study in the emergency setting
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0263149
Abstract: Objective N-acetylcysteine has a demonstrated role as an adjunctive therapy in psychotic and affective disorders as a treatment to reduce symptoms of Bipolar Affective Disorder, Major Depressive Disorder and Schizophrenia. However, its potential as a… read more here.
Keywords: rapidly acting; suicidal agent; anti suicidal; naturalistic study ... See more keywords