Cardamonin inhibits cell proliferation by caspase-mediated cleavage of Raptor
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01986-z
Abstract: The antiproliferative effect of cardamonin on mTORC1 is related with downregulation of Raptor. We investigated the mechanism that cardamonin decreases Raptor expression through caspase-mediated protein degradation. SKOV3 cells and HeLa cells were pretreated with caspase… read more here.
Keywords: cardamonin; caspase; caspase mediated; cleavage ... See more keywords
Implications of farmland expansion for species abundance, richness and mean body mass in African raptor communities
Sign Up to like & getrecommendations! Published in 2019 at "Biological Conservation"
DOI: 10.1016/j.biocon.2019.03.039
Abstract: Abstract Globally, conversion of natural habitats to farmland poses the greatest extinction risk to birds, its consequences being especially pervasive in the case of large predators and scavengers, whose declines may trigger extensive cascading effects.… read more here.
Keywords: raptor; land; body mass; expansion ... See more keywords
Upregulation of Akt/Raptor signaling is associated with rapamycin resistance of breast cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.109243
Abstract: mTOR inhibitors are considered today to be one of the most promising anticancer drugs. Here to study the mechanism of the acquired resistance of MCF-7 breast cancer cells to mTOR inhibitors two different models of… read more here.
Keywords: mtor inhibitors; breast cancer; resistance; raptor ... See more keywords
The prevalence of Leucocytozoon spp. in nestlings of three wild raptor species including implications on haematological and blood chemistry values
Sign Up to like & getrecommendations! Published in 2021 at "International Journal for Parasitology: Parasites and Wildlife"
DOI: 10.1016/j.ijppaw.2021.10.009
Abstract: Leucocytozoonosis is a vector-borne infection of birds, caused by members of the haemosporidian genus Leucocytozoon. The clinical presentation may range from asymptomatic to severe disease. Consequences of Leucocytozoon infection on blood profiles remain to be… read more here.
Keywords: leucocytozoon spp; leucocytozoon; chemistry; blood chemistry ... See more keywords
Raptor determines β-cell identity and plasticity independent of hyperglycemia in mice
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15935-0
Abstract: Compromised β-cell identity is emerging as an important contributor to β-cell failure in diabetes; however, the precise mechanism independent of hyperglycemia is under investigation. We have previously reported that mTORC1/Raptor regulates functional maturation in β-cells.… read more here.
Keywords: cell; cell identity; independent hyperglycemia; identity ... See more keywords
Loss of Raptor induces Sertoli cells into an undifferentiated state in mice
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac104
Abstract: Abstract In mammals, testis development is triggered by the expression of the sex-determining Y-chromosome gene SRY to commit the Sertoli cell (SC) fate at gonadal sex determination in the fetus. Several genes have been identified… read more here.
Keywords: cell; cells undifferentiated; undifferentiated state; raptor ... See more keywords
Clock-linked genes underlie seasonal migratory timing in a diurnal raptor
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the Royal Society B: Biological Sciences"
DOI: 10.1098/rspb.2021.2507
Abstract: Seasonal migration is a dynamic natural phenomenon that allows organisms to exploit favourable habitats across the annual cycle. While the morphological, physiological and behavioural changes associated with migratory behaviour are well characterized, the genetic basis… read more here.
Keywords: migratory; linked genes; migratory timing; clock linked ... See more keywords
Generation of raptor diversity in Europe: linking speciation with climate changes and the ability to migrate
Sign Up to like & getrecommendations! Published in 2022 at "PeerJ"
DOI: 10.1101/2022.03.29.486263
Abstract: Aim Europe should be considered as a diversity hotspot for diurnal raptors, but just during the breeding season, as it holds the higher proportion of transcontinental migratory species of any landmass, and the area becomes… read more here.
Keywords: migratory; migrate; diversity; breeding season ... See more keywords
Reliable Random Access for Decentralized UAV Networks Based on Raptor Codes
Sign Up to like & getrecommendations! Published in 2021 at "IEEE Internet of Things Journal"
DOI: 10.1109/jiot.2021.3074737
Abstract: In this article, we propose the Raptor coded random access (RCRA) scheme to enable reliable transmission in the decentralized unmanned aerial vehicle (UAV) network. The considered network is composed of several overlapped random access systems… read more here.
Keywords: raptor; random access; access; reliable random ... See more keywords
Bounds on the Error Probability of Raptor Codes Under Maximum Likelihood Decoding
Sign Up to like & getrecommendations! Published in 2021 at "IEEE Transactions on Information Theory"
DOI: 10.1109/tit.2020.3049061
Abstract: In this paper upper and lower bounds on the probability of decoding failure under maximum likelihood decoding are derived for different (nonbinary) Raptor code constructions. In particular four different constructions are considered; (i) the standard… read more here.
Keywords: maximum likelihood; raptor codes; raptor; likelihood decoding ... See more keywords
mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner.
Sign Up to like & getrecommendations! Published in 2020 at "Endocrinology"
DOI: 10.1210/endocr/bqaa041
Abstract: Mechanistic target of rapamycin (mTOR) pathway plays a role in features common to both excess salt/aldosterone and cardiovascular/renal diseases. Dietary sodium can upregulate mTORC1 signaling in cardiac and renal tissue, and inhibition of mTOR can… read more here.
Keywords: aldosterone; volume; volume homeostatic; sodium ... See more keywords