Development and validation of a droplet digital PCR assay for the evaluation of PML-RARα fusion transcripts in acute promyelocytic leukemia.
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DOI: 10.1016/j.mcp.2020.101617
Abstract: Acute promyelocytic leukemia (APL) is an aggressive disease that requires prompt treatment. Promyelocytic leukemia protein-retinoic acid receptor α (PML-RARα) fusion genes resulting from reciprocal translocation are considered a molecular basis for diagnosing APL. Moreover, PML-RARα… read more here.
Keywords: pml; promyelocytic leukemia; rar fusion; pml rar ... See more keywords