Widespread position-specific conservation of synonymous rare codons within coding sequences
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005531
Abstract: Synonymous rare codons are considered to be sub-optimal for gene expression because they are translated more slowly than common codons. Yet surprisingly, many protein coding sequences include large clusters of synonymous rare codons. Rare codons… read more here.
Keywords: within coding; rare codon; rare codons; synonymous rare ... See more keywords
Distinct responses to rare codons in select Drosophila tissues
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DOI: 10.7554/elife.76893
Abstract: Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression. Here, we use codon-modified reporters to perform… read more here.
Keywords: codon usage; codon; distinct responses; rare codons ... See more keywords