Genome-wide Analysis of Rare Haplotypes Associated with Breast Cancer Risk.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-1888
Abstract: Numerous common genetic variants have been linked to breast cancer (BCa) risk, but they only partially explain the total BCa heritability. Inference from Nordic population-based twin data indicates rare high-risk loci as the chief determinant… read more here.
Keywords: bca; rare haplotypes; breast cancer; risk ... See more keywords
Bivariate quantitative Bayesian LASSO for detecting association of rare haplotypes with two correlated continuous phenotypes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1104727
Abstract: In genetic association studies, the multivariate analysis of correlated phenotypes offers statistical and biological advantages compared to analyzing one phenotype at a time. The joint analysis utilizes additional information contained in the correlation and avoids… read more here.
Keywords: rare haplotypes; continuous phenotypes; phenotypes bivariate; association ... See more keywords