Funding for rare tumor research in China under discussion
Sign Up to like & getrecommendations! Published in 2021 at "National Science Review"
DOI: 10.1093/nsr/nwab106
Abstract: ‘Throughout the world, medical research has never been equitable. Diseases with more patients and better publicity always grasp more attention, get more funding, and are better studied,’ saidWenmingWu, a digestive surgeon and the vice-President of… read more here.
Keywords: rare tumors; rare tumor; funding; tumor research ... See more keywords
Decrease in tumor content assessed in biopsies is associated with improved treatment outcome response to pembrolizumab in patients with rare tumors
Sign Up to like & getrecommendations! Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-000665
Abstract: Background Decreased tumor content (TC) in resection specimens after neoadjuvant therapy is used to predict prognosis. We investigated whether TC assessed in biopsy specimens or the shift in TC from baseline to on-treatment can be… read more here.
Keywords: baseline treatment; response; treatment; patients rare ... See more keywords
Ipilimumab and Nivolumab in Rare Tumors S1609: Neuroendocrine—Letter
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-20-0443
Abstract: Patel and colleagues report the results of the basket trial (DART) studying the checkpoint inhibitors combination, ipilimumab plus nivolumab, in a cohort of patients with neuroendocrine neoplasms (NEN; ref. [1][1]). We commend the authors for… read more here.
Keywords: s1609 neuroendocrine; neuroendocrine letter; rare tumors; ipilimumab nivolumab ... See more keywords
Abstract 4512: My Pediatric and Adult Rare Tumor Network (MyPART): integrating longitudinal, clinical, molecular, and patient-reported outcomes for rare tumors
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4512
Abstract: Background: Rare tumors are defined as read more here.
Keywords: adult rare; rare tumor; rare tumors; pediatric adult ... See more keywords
KRAS Mutation in Rare Tumors: A Landscape Analysis of 3453 Chinese Patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.831382
Abstract: KRAS is the most commonly mutated oncogene in human cancers. Targeted therapy and immunotherapy for this gene have made remarkable progress in recent years. However, comprehensive molecular landscape analysis of KRAS in rare tumors is… read more here.
Keywords: rare tumors; landscape analysis; mutation; kras mutations ... See more keywords
Small Molecules in Rare Tumors: Emerging Role of MicroRNAs in GIST
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19020397
Abstract: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of gastrointestinal tract. GISTs have very different clinical phenotypes and underlying molecular characteristics that are not yet completely understood. microRNAs (miRNAs) have been shown to… read more here.
Keywords: emerging role; molecules rare; small molecules; role ... See more keywords