Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes
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DOI: 10.1038/s41467-024-46795-7
Abstract: Understanding the function of rare non-coding variants represents a significant challenge. Using MapUTR, a screening method, we studied the function of rare 3′ UTR variants affecting mRNA abundance post-transcriptionally. Among 17,301 rare gnomAD variants, an… read more here.
Keywords: utr variants; cancer; rare utr; mrna abundance ... See more keywords