To rarefy or not to rarefy: robustness and efficiency trade-offs of rarefying microbiome data.
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DOI: 10.1093/bioinformatics/btac127
Abstract: MOTIVATION Microbiome datasets provide rich information about microbial communities. However, vast library size variations across samples present great challenges for proper statistical comparisons. To deal with these challenges, rarefaction is often used in practice as… read more here.
Keywords: microbiome data; rarefying microbiome; rarefy; efficiency ... See more keywords