Ras-Mediated Activation of the Raf Family Kinases.
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DOI: 10.1101/cshperspect.a033746
Abstract: The extracellular signal-regulated kinase (ERK) cascade comprised of the Raf, MEK, and ERK protein kinases constitutes a key effector cascade used by the Ras GTPases to relay signals regulating cell growth, survival, proliferation, and differentiation.… read more here.
Keywords: activation raf; ras mediated; raf activation; raf family ... See more keywords
RAF Binding Preferences Dictate RAS-Mediated Tumorigenesis.
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DOI: 10.1158/2159-8290.cd-rw2019-158
Abstract: Distinct binding between RAS and RAF family members determines RAS signaling. read more here.
Keywords: mediated tumorigenesis; binding preferences; raf binding; preferences dictate ... See more keywords