MicroRNA-15a/16-1 Prevents Hepatocellular Carcinoma by Disrupting the Communication between Kupffer Cells and Tregs.
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DOI: 10.1053/j.gastro.2021.10.015
Abstract: BACKGROUND & AIMS Hepatocellular carcinoma (HCC) is characterized by intratumoral accumulation of regulatory T-cells (Tregs), which suppresses antitumor immunity. This study was designed to investigate how microRNAs regulate immunosuppression in HCC. METHODS FVB/NJ mice were… read more here.
Keywords: ras myc; akt ras; hepatocellular carcinoma; hcc ... See more keywords