Role of MiR-27a-3p in Intervertebral Disc Degeneration through Targeting RASSF5 via MST1/LATS1 and RAS/RAC1 Signaling Pathway
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DOI: 10.1155/2022/4457673
Abstract: Background The apoptosis of nucleus pulposus (NP) cells reduces the number of nucleus pulposus cells in intervertebral disc tissue, resulting in intervertebral disc degeneration (IDD). MicroRNAs (miRNAs) play an important regulatory role in abnormal cell… read more here.
Keywords: rassf5; apoptosis; ras rac1; lats1 ras ... See more keywords
IRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway
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DOI: 10.2147/cmar.s186236
Abstract: Background Interferon regulatory factor 1 (IRF1) plays a role in the immune response, cellular necrosis, DNA damage, and DNA repair, offering an attractive target for anticancer treatment. However, little is known about the role of… read more here.
Keywords: expression; metastasis; ras rac1; rac1 pathway ... See more keywords