Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination
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DOI: 10.1126/science.aap7607
Abstract: Regulation of RAS by ubiquitination The protein LZTR1 is mutated in human cancers and developmental diseases. Work from two groups now converges to implicate the protein in regulating signaling by the small guanosine triphosphatase RAS.… read more here.
Keywords: mutations lztr1; disease; ras ubiquitination; human disease ... See more keywords