Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling
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DOI: 10.1016/j.jmb.2020.01.002
Abstract: Abstract Ras recruits and activates effectors that transmit receptor-initiated signals. Monomeric Ras can bind Raf; however, Raf's activation requires dimerization, which can be facilitated by Ras dimerization. Previously, we showed that active K-Ras4B dimerizes in… read more here.
Keywords: kinase; ras4b; dimerization; mitogen activated ... See more keywords