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EPHB4-RASA1-Mediated Negative Regulation of Ras-MAPK Signaling in the Vasculature: Implications for the Treatment of EPHB4- and RASA1-Related Vascular Anomalies in Humans

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Published in 2023 at "Pharmaceuticals"

DOI: 10.3390/ph16020165

Abstract: Ephrin receptors constitute a large family of receptor tyrosine kinases in mammals that through interaction with cell surface-anchored ephrin ligands regulate multiple different cellular responses in numerous cell types and tissues. In the cardiovascular system,… read more here.

Keywords: ras mapk; anomalies humans; vascular anomalies; rasa1 ... See more keywords