Ha-RasV12-Induced Multilayer Cellular Aggregates Is Mediated by Rac1 Activation Rather Than YAP Activation
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DOI: 10.3390/biomedicines10050977
Abstract: We demonstrate that Ha-RasV12 overexpression induces the nuclear translocation of Hippo effector Yes-associated protein (YAP) in MDCK cells via the hippo-independent pathway at the confluent stage. Ha-RasV12 overexpression leads to the downregulation of Caveolin-1 (Cav1)… read more here.
Keywords: junction integrity; rasv12; rasv12 induced; cellular aggregates ... See more keywords