Chronic effects of platinum(IV) complex and its diamine ligand on rat heart function: comparison with cisplatin
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03533-8
Abstract: The aim of the present study was to compare the cardiodynamic parameters in the isolated rat heart in animals chronically treated with cisplatin, platinum(IV) complex and its diamine ligand. Sixty Wistar albino rats (8 weeks old)… read more here.
Keywords: platinum; heart; rat heart; function ... See more keywords
Toxicity of new synthetic amphetamine drug mephedrone On Rat Heart mitochondria: a warning for its abuse
Sign Up to like & getrecommendations! Published in 2018 at "Xenobiotica"
DOI: 10.1080/00498254.2017.1401753
Abstract: Abstract 1. Mephedrone, a new and popular amphetamine drug, is widely abused and is still legal in some parts around the world. Little data on mechanisms involved in mephedrone induced cardiotoxicity are available. 2. Therefore, we decided… read more here.
Keywords: heart; mephedrone; amphetamine drug; heart mitochondria ... See more keywords
Evidence of Altered Mitochondrial Protein Expression After Chronic Ethanol Consumption in the Aged Estrogen‐Deficient Female Rat Heart
Sign Up to like & getrecommendations! Published in 2017 at "Alcoholism: Clinical and Experimental Research"
DOI: 10.1111/acer.13421
Abstract: BACKGROUND Estrogen loss has been implicated to increase the risk of alcoholic cardiomyopathy in postmenopausal women. The purpose of this study was to identify novel mitochondrial protein targets for the treatment of alcoholic cardiomyopathy in… read more here.
Keywords: protein expression; mitochondrial protein; heart; rat heart ... See more keywords
Hemodynamic and electromechanical effects of paraquat in rat heart
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0234591
Abstract: Paraquat (PQ) is a highly lethal herbicide. Ingestion of large quantities of PQ usually results in cardiovascular collapse and eventual mortality. Recent pieces of evidence indicate possible involvement of oxidative stress- and inflammation-related factors in… read more here.
Keywords: heart; electromechanical effects; effects paraquat; hemodynamic electromechanical ... See more keywords
Glucagon and exenatide improve contractile recovery following ischaemia/reperfusion in the isolated perfused rat heart
Sign Up to like & getrecommendations! Published in 2023 at "Physiological Reports"
DOI: 10.14814/phy2.15597
Abstract: The inotropic effects of glucagon have been recognized for many years, but it has remained unclear whether glucagon signaling is beneficial to cardiac function. We evaluated the effects of glucagon alone and in combination with… read more here.
Keywords: reperfusion; glucagon; heart; isolated perfused ... See more keywords
Neonatal Rat Heart Response to Pressure Overload.
Sign Up to like & getrecommendations! Published in 2017 at "International heart journal"
DOI: 10.1536/ihj.17-006
Abstract: H eart failure is caused by myocyte loss secondary to necrosis and/or apoptosis due to injury or excess workload, and is further complicated by adverse remodeling. Recently, there is increasing evidence refuting the traditional notion… read more here.
Keywords: heart; response pressure; neonatal rat; rat heart ... See more keywords
6-NitroDopamine is an endogenous modulator of rat heart chronotropism.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.2139/ssrn.4151645
Abstract: 6-Nitrodopamine (6-ND) is released by rat vas deferens and exerts a potent contractile response that is antagonized by tricyclic antidepressants and α1-, β1- and β1/β2-adrenoceptor antagonists. The release of 6-ND, noradrenaline, adrenaline and dopamine from… read more here.
Keywords: name; modulator rat; atrial frequency; heart ... See more keywords
Nandrolone Decanoate and Swimming Affects Cardiodynamic and Morphometric Parameters in the Isolated Rat Heart
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12081242
Abstract: (1) Background: The aim of this study was to show the effects of swimming and nandrolone administration on cardiodynamic and morphometric parameters of the isolated rat heart. (2) The study included 72 Wistar rats, divided… read more here.
Keywords: cardiodynamic morphometric; parameters isolated; heart; isolated rat ... See more keywords
Optimization of Complete Rat Heart Decellularization Using Artificial Neural Networks
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13010079
Abstract: Whole organ decellularization techniques have facilitated the fabrication of extracellular matrices (ECMs) for engineering new organs. Unfortunately, there is no objective gold standard evaluation of the scaffold without applying a destructive method such as histological… read more here.
Keywords: optimization complete; neural networks; complete rat; rat heart ... See more keywords
Mechanical effects of ranolazine on normal and diabetic-isolated rat heart
Sign Up to like & getrecommendations! Published in 2021 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.314825
Abstract: Background and purpose: Diabetic cardiomyopathy is a complication of diabetes defined as cardiac dysfunction without the involvement of pericardial vessels, hypertension, or cardiac valve disorders. Ranolazine, an antianginal drug, acts through blocking of cardiac late… read more here.
Keywords: normal diabetic; normal hearts; effects ranolazine; isolated rat ... See more keywords