Articles with "rat hippocampus" as a keyword



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Lipidomic changes in the rat hippocampus following cocaine conditioning, extinction, and reinstatement of drug‐seeking

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Published in 2019 at "Brain and Behavior"

DOI: 10.1002/brb3.1451

Abstract: Cocaine dependence affects millions of individuals worldwide; however, there are no pharmacotherapeutic and/or diagnostic solutions. Recent evidence suggests a role for lipid signaling in the development and maintenance of addiction, highlighting the need to understand… read more here.

Keywords: changes rat; hippocampus following; lipidomic changes; following cocaine ... See more keywords
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Sodium channel subtypes are differentially localized to pre‐ and post‐synaptic sites in rat hippocampus

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Published in 2017 at "Journal of Comparative Neurology"

DOI: 10.1002/cne.24291

Abstract: Voltage‐gated Na+ channels (Nav) modulate neuronal excitability, but the roles of the various Nav subtypes in specific neuronal functions such as synaptic transmission are unclear. We investigated expression of the three major brain Nav subtypes… read more here.

Keywords: nav subtypes; axon terminals; pre post; rat hippocampus ... See more keywords
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Effects of mobile phone electromagnetic radiation on rat hippocampus proteome

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Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23447

Abstract: Worldwide, the number of mobile phone users has increased from 5.57 billion in 2011 to 6.8 billion in 2019. However, short‐ and long‐term impact of the electromagnetic radiation emitting from mobile phones on tissue homeostasis… read more here.

Keywords: mobile phone; hippocampus proteome; rat hippocampus; phone ... See more keywords
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Dichloroacetic acid-induced dysfunction in rat hippocampus and the protective effect of curcumin.

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Published in 2021 at "Metabolic brain disease"

DOI: 10.1007/s11011-020-00657-5

Abstract: The present study was designed to evaluate the role of cAMP-PKA-CREB signaling in mediating the neuroprotective effects of curcumin against DCAA-induced oxidative stress, inflammation and impaired synaptic plasticity in rats. Sixty Sprague-Dawley rats were randomly… read more here.

Keywords: camp; creb; dcaa; dcaa induced ... See more keywords
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WITHDRAWN: Developmental regulation and lateralization of GABA receptors in the rat hippocampus

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Published in 2019 at "International Journal of Developmental Neuroscience"

DOI: 10.1016/j.ijdevneu.2019.01.002

Abstract: GABA is the chief inhibitory neurotransmitter in the adult brain. However, in the developing brain it acts as an excitatory transmitter causing depolarization. Thereby, activates calcium-dependent processes that are crucial for brain development. Accordingly, GABA… read more here.

Keywords: rat hippocampus; brain; development; gaba receptors ... See more keywords
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Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats.

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Published in 2019 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2019.06.043

Abstract: Sensitive and comprehensive measurement of systemic metabolites of tryptophan, phenylalanine and glutamate metabolism in biological samples is effective for understanding the pathogenesis of depression and other neurological diseases. Therefore, this study developed an underivatized liquid… read more here.

Keywords: hippocampus; plasma urine; hippocampus plasma; acid ... See more keywords
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Low-level laser therapy for beta amyloid toxicity in rat hippocampus

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Published in 2017 at "Neurobiology of Aging"

DOI: 10.1016/j.neurobiolaging.2016.10.003

Abstract: Beta amyloid (Aβ) is well accepted to play a central role in the pathogenesis of Alzheimer's disease (AD). The present work evaluated the therapeutic effects of low-level laser irradiation (LLI) on Aβ-induced neurotoxicity in rat… read more here.

Keywords: beta amyloid; pathology; suppressed induced; level laser ... See more keywords
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Paraoxon-induced damage in rat hippocampus is associated with alterations in the expression of apoptosis-related proteins.

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Published in 2020 at "Pesticide biochemistry and physiology"

DOI: 10.1016/j.pestbp.2020.104580

Abstract: To determine the possible role of apoptosis in the development of paraoxon-induced brain damage, we evaluated expression of apoptosis-related proteins, the extent of neuronal damage, and activation of astrocytes in rat hippocampus. Adult male Wistar… read more here.

Keywords: hippocampus; expression apoptosis; related proteins; apoptosis related ... See more keywords
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Melatonin Attenuates Methotrexate-Induced Reduction of Antioxidant Activity Related to Decreases of Neurogenesis in Adult Rat Hippocampus and Prefrontal Cortex

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/1596362

Abstract: Previous studies have revealed that the side effects of anticancer drugs induce a decrease of neurogenesis. Methotrexate (MTX), one of anticancer drugs, can induce lipid peroxidation as an indicator of oxidative stress in the brain.… read more here.

Keywords: mtx; adult rat; hippocampus prefrontal; rat hippocampus ... See more keywords
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Selective modulation of neuronal firing by pulse stimulations with different frequencies in rat hippocampus

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Published in 2019 at "BioMedical Engineering OnLine"

DOI: 10.1186/s12938-019-0700-z

Abstract: BackgroundDeep brain stimulation (DBS) has a good prospect for treating many brain diseases. Recent studies have shown that axonal activation induced by pulse stimulations may play an important role in DBS therapies through wide projections… read more here.

Keywords: stimulations different; frequency; stimulation; firing ... See more keywords
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The Lentiviral Vector Pseudotyped by Modified Rabies Glycoprotein Does Not Cause Reactive Gliosis and Neurodegeneration in Rat Hippocampus

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Published in 2019 at "Iranian biomedical journal"

DOI: 10.29252/ibj.23.5.3

Abstract: Background A human immunodeficiency virus type 1 (HIV-1)-based lentiviral vector (LV) pseudotyped by a variant of rabies envelope glycoprotein, FUG-B2, has previously been prepared and used in transfection of hippocampal CA1 ("Cornu Ammonis" area 1)… read more here.

Keywords: vector; reactive gliosis; vector pseudotyped; rat hippocampus ... See more keywords