Articles with "rat isolated" as a keyword



Effect of Matricaria chamomilla hydro-alcoholic and flavonoids rich extracts on rat isolated uterus

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Published in 2020 at "Journal of HerbMed Pharmacology"

DOI: 10.15171/jhp.2020.05

Abstract: Introduction: Pharmacological studies confirm antispasmodic activities of chamomile (Matricaria chamomilla) extract on intestinal smooth muscles and it has been suggested that chamomile increases uterus tone, but so far there is no scientific studies which support… read more here.

Keywords: isolated uterus; chamomilla; rat isolated; hydro alcoholic ... See more keywords

Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects.

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Published in 2022 at "Vascular pharmacology"

DOI: 10.2139/ssrn.4197599

Abstract: Phosphodiesterase 5 (PDE5) inhibitors are an attractive option among the currently available therapies in the management of pulmonary arterial hypertension (PAH). Good selectivity for PDE5 is associated with reduced side effects and greater vasorelaxant effect… read more here.

Keywords: vasorelaxant effect; rat isolated; effect; quinazoline based ... See more keywords

GKT137831 and hydrogen peroxide increase the release of 6-nitrodopamine from the human umbilical artery, rat-isolated right atrium, and rat-isolated vas deferens

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Published in 2024 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2024.1348876

Abstract: Introduction: The human umbilical artery (HUA), rat-isolated right atrium, and rat-isolated vas deferens present a basal release of 6-nitrodopamine (6-ND). The basal release of 6-ND from these tissues was significantly decreased (but not abolished) when… read more here.

Keywords: hua; basal release; release; rat isolated ... See more keywords