High-pressure carbon monoxide preserves rat kidney grafts from apoptosis and inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Laboratory Investigation"
DOI: 10.1038/labinvest.2016.157
Abstract: Renal ischemia–reperfusion (I/R) injury is unavoidable in kidney transplantation (KTx) and frequently influences both short- and long-term allograft survival. Carbon monoxide (CO) has attracted attention as a medical gas with anti-inflammatory and anti-apoptotic effects. We… read more here.
Keywords: kidney grafts; carbon monoxide; high pressure; rat kidney ... See more keywords
Ultrasound localization microscopy to image and assess microvasculature in a rat kidney
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13676-7
Abstract: The recent development of ultrasound localization microscopy, where individual microbubbles (contrast agents) are detected and tracked within the vasculature, provides new opportunities for imaging the vasculature of entire organs with a spatial resolution below the… read more here.
Keywords: rat kidney; ultrasound localization; localization microscopy; microscopy ... See more keywords
Engineering the vasculature of decellularized rat kidney scaffolds using human induced pluripotent stem cell-derived endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44393-y
Abstract: Generating new kidneys using tissue engineering technologies is an innovative strategy for overcoming the shortage of donor organs for transplantation. Here we report how to efficiently engineer the kidney vasculature of decellularized rat kidney scaffolds… read more here.
Keywords: vasculature decellularized; decellularized rat; rat kidney; cell ... See more keywords
Dietary sodium enhances the expression of SLC4 family transporters, IRBIT, L-IRBIT, and PP1 in rat kidney: Insights into the molecular mechanism for renal sodium handling
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1154694
Abstract: The kidney plays a central role in maintaining the fluid and electrolyte homeostasis in the body. Bicarbonate transporters NBCn1, NBCn2, and AE2 are expressed at the basolateral membrane of the medullary thick ascending limb (mTAL).… read more here.
Keywords: kidney; nbcn2 ae2; sodium; nbcn1 nbcn2 ... See more keywords
Unexpected Enhancement of Cytotoxicity of Cisplatin in a Rat Kidney Proximal Tubular Cell Line Overexpressing Mitochondrial Glutathione Transport Activity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23041993
Abstract: In previous studies, we identified the two principal transporters that mediate the uptake of glutathione (GSH) from cytoplasm into the mitochondrial matrix of rat kidney proximal tubular cells. We hypothesized that genetic modulation of transporter… read more here.
Keywords: proximal tubular; kidney proximal; cisplatin; glutathione ... See more keywords