Cell release during perfusion reflects cold ischemic injury in rat livers
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-57589-4
Abstract: The global shortage of donor organs has made it crucial to deeply understand and better predict donor liver viability. However, biomarkers that effectively assess viability of marginal grafts for organ transplantation are currently lacking. Here,… read more here.
Keywords: cell release; cold ischemic; rat livers; ischemic injury ... See more keywords
The effect of blood cells retained in rat livers during static cold storage on viability outcomes during normothermic machine perfusion
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DOI: 10.1038/s41598-021-02417-6
Abstract: In transplantation, livers are transported to recipients using static cold storage (SCS), whereby livers are exposed to cold ischemic injury that contribute to post-transplant risk factors. We hypothesized that flushing organs during procurement with cold… read more here.
Keywords: rat livers; cold storage; normothermic machine; static cold ... See more keywords
4 in 1: Antibody‐free protocol for isolating the main hepatic cells from healthy and cirrhotic single rat livers
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13988
Abstract: Liver cells isolated from pre‐clinical models are essential tools for studying liver (patho)physiology, and also for screening new therapeutic options. We aimed at developing a new antibody‐free isolation method able to obtain the four main… read more here.
Keywords: antibody free; rat livers; cirrhotic single; main hepatic ... See more keywords