Combined detection of serum CTX-II and C2C in a rat model of ACLT-induced osteoarthritis.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13613
Abstract: Osteoarthritis (OA) is a chronic degenerative bone and joint disease that often occurs in aging animals. Currently, there are still no biomarkers that can effectively diagnose OA in the early stage. To identify possible biomarkers,… read more here.
Keywords: aclt induced; serum; c2c; ctx c2c ... See more keywords
Full-Thickness Heart Repair with an Engineered Multilayered Myocardial Patch in Rat Model.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201600549
Abstract: In a rat model of right free wall replacement, the transplantation of an engineered multilayered myocardial patch fabricated from a polycaprolactone membrane supporting a chitosan/heart matrix hydrogel induces significant muscular and vascular remodeling and results… read more here.
Keywords: patch; myocardial patch; multilayered myocardial; engineered multilayered ... See more keywords
Phenotypic characterization of frontal cortex microglia in a rat model of post‐traumatic stress disorder
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2011
Abstract: Post‐traumatic stress disorder (PTSD) is an anxiety disorder induced by psychologically traumatic events. Using a rat model, this study aimed to determine whether psychological trauma alters relative expression between pro‐inflammatory and anti‐inflammatory markers in microglia.… read more here.
Keywords: post traumatic; stress disorder; disorder; traumatic stress ... See more keywords
Dimorphic evaluation of hippocampal changes in rat model of demyelination: A comparative functional, morphometric, and histological study
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2723
Abstract: Multiple sclerosis (MS) is the most common autoimmune disease. Progressive depletion of the brain and spinal cord tissue appears at the onset of the disease. Several studies have shown the increased size of the ventricles… read more here.
Keywords: changes rat; brain; evaluation hippocampal; hippocampal changes ... See more keywords
Learning and memory disabilities in IUGR babies: Functional and molecular analysis in a rat model
Sign Up to like & getrecommendations! Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.631
Abstract: Intrauterine growth restriction (IUGR) is the failure of the fetus to achieve its inherent growth potential, and it has frequently been associated with neurodevelopmental problems in childhood. Neurological disorders are mostly associated with IUGR babies… read more here.
Keywords: learning memory; model; iugr babies; memory disabilities ... See more keywords
Nrf2 mediates the antinociceptive activity of dexmedetomidine in an acute inflammatory visceral pain rat model by activating the NF‐κB sensor
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3456
Abstract: Dexmedetomidine (DEX) is a highly selective α2 adrenoceptor agonist. In this study, we evaluated the antalgic effect of DEX on acetic acid–induced acute inflammatory visceral pain (AIVP) in rats. Additionally, we evaluated the role of… read more here.
Keywords: acute inflammatory; dex; nrf2; model ... See more keywords
BML‐111 inhibits osteoclast differentiation by suppressing the MAPK and NF‐κB pathways, alleviating deterioration of the knee joints in a CIA rat model
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11990
Abstract: Irreversible destruction of joints is the hallmark of rheumatoid arthritis (RA). Osteoclasts are the only bone‐resorbing cells and play an important role in joint rebuilding. BML‐111 (5(S),6(R),7‐trihydroxyheptanoic acid methyl ester, C8H16O5) is a synthetic lipoxin… read more here.
Keywords: differentiation; rat model; knee joints; bml 111 ... See more keywords
The capsaicinoid nonivamide suppresses the inflammatory response and attenuates the progression of steatosis in a NAFLD‐rat model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23279
Abstract: Nonalcoholic fatty liver disease (NAFLD) is relatively associated with comorbidities in obesity and metabolic inflammation. Low‐grade inflammation following the high‐fat diet (HFD)‐induced NAFLD can promote the development of nonalcoholic steatohepatitis (NASH) through particularly liver‐resident immune… read more here.
Keywords: pava; rat model; nafld rat;
MT‐102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12537
Abstract: Cachexia, a common manifestation of malignant cancer, is associated with wasting of skeletal muscle and fat tissue. In this study, we investigated the effects of a new first in class anabolic catabolic transforming agent on… read more here.
Keywords: cachexia; tissue; cancer cachexia; cancer ... See more keywords
Reinforced behavioral variability in the valproate rat model of autism spectrum disorder.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the experimental analysis of behavior"
DOI: 10.1002/jeab.760
Abstract: Individuals diagnosed with autism spectrum disorder (ASD) tend to display restricted, repetitive behaviors and deficits in social interaction. Rats exposed to valproate (VPA) in utero have been shown to model symptoms of ASD. In previous… read more here.
Keywords: variability required; variability; rat model; model ... See more keywords
Long‐term outcomes of arterial ischemia or venous occlusion on vascularized groin lymph nodes in a rat model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26980
Abstract: This study investigated the long‐term effects of arterial ischemia and venous occlusion on lymph node drainage function in a rat model. read more here.
Keywords: long term; ischemia venous; arterial ischemia; venous occlusion ... See more keywords