Combined detection of serum CTX-II and C2C in a rat model of ACLT-induced osteoarthritis.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13613
Abstract: Osteoarthritis (OA) is a chronic degenerative bone and joint disease that often occurs in aging animals. Currently, there are still no biomarkers that can effectively diagnose OA in the early stage. To identify possible biomarkers,… read more here.
Keywords: aclt induced; serum; c2c; ctx c2c ... See more keywords
Full-Thickness Heart Repair with an Engineered Multilayered Myocardial Patch in Rat Model.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201600549
Abstract: In a rat model of right free wall replacement, the transplantation of an engineered multilayered myocardial patch fabricated from a polycaprolactone membrane supporting a chitosan/heart matrix hydrogel induces significant muscular and vascular remodeling and results… read more here.
Keywords: patch; myocardial patch; multilayered myocardial; engineered multilayered ... See more keywords
ALKBH5 modulates bone cancer pain in a rat model by suppressing NR2B expression
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2601
Abstract: Currently, the clinical treatment of bone cancer pain (BCP) is mainly related to its pathogenesis. The aim of the present study was to elucidate the potential role of N6‐methyladenosine (m6A) in BCP in the spinal… read more here.
Keywords: bone cancer; alkbh5; rat model; expression ... See more keywords
Phenotypic characterization of frontal cortex microglia in a rat model of post‐traumatic stress disorder
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2011
Abstract: Post‐traumatic stress disorder (PTSD) is an anxiety disorder induced by psychologically traumatic events. Using a rat model, this study aimed to determine whether psychological trauma alters relative expression between pro‐inflammatory and anti‐inflammatory markers in microglia.… read more here.
Keywords: post traumatic; stress disorder; disorder; traumatic stress ... See more keywords
Dimorphic evaluation of hippocampal changes in rat model of demyelination: A comparative functional, morphometric, and histological study
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2723
Abstract: Multiple sclerosis (MS) is the most common autoimmune disease. Progressive depletion of the brain and spinal cord tissue appears at the onset of the disease. Several studies have shown the increased size of the ventricles… read more here.
Keywords: changes rat; brain; evaluation hippocampal; hippocampal changes ... See more keywords
Learning and memory disabilities in IUGR babies: Functional and molecular analysis in a rat model
Sign Up to like & getrecommendations! Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.631
Abstract: Intrauterine growth restriction (IUGR) is the failure of the fetus to achieve its inherent growth potential, and it has frequently been associated with neurodevelopmental problems in childhood. Neurological disorders are mostly associated with IUGR babies… read more here.
Keywords: learning memory; model; iugr babies; memory disabilities ... See more keywords
Nrf2 mediates the antinociceptive activity of dexmedetomidine in an acute inflammatory visceral pain rat model by activating the NF‐κB sensor
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3456
Abstract: Dexmedetomidine (DEX) is a highly selective α2 adrenoceptor agonist. In this study, we evaluated the antalgic effect of DEX on acetic acid–induced acute inflammatory visceral pain (AIVP) in rats. Additionally, we evaluated the role of… read more here.
Keywords: acute inflammatory; dex; nrf2; model ... See more keywords
BML‐111 inhibits osteoclast differentiation by suppressing the MAPK and NF‐κB pathways, alleviating deterioration of the knee joints in a CIA rat model
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11990
Abstract: Irreversible destruction of joints is the hallmark of rheumatoid arthritis (RA). Osteoclasts are the only bone‐resorbing cells and play an important role in joint rebuilding. BML‐111 (5(S),6(R),7‐trihydroxyheptanoic acid methyl ester, C8H16O5) is a synthetic lipoxin… read more here.
Keywords: differentiation; rat model; knee joints; bml 111 ... See more keywords
Developmental Trajectory of Autistic-Like Behaviors in a Prenatal Valproic Acid Rat Model of Autism.
Sign Up to like & getrecommendations! Published in 2024 at "Developmental psychobiology"
DOI: 10.1002/dev.70008
Abstract: Autism spectrum disorders (ASDs) are characterized by deficits in social functioning, stereotyped patterns of behaviors, narrowed interests, and elevated anxiety. Certain ASD symptoms can persist, whereas others may improve throughout the lifespan, but the specific… read more here.
Keywords: vpa; recognition; model; rat model ... See more keywords
Multiorgan characterization of inflammasome component expression in a rat model of advanced heart failure
Sign Up to like & getrecommendations! Published in 2025 at "ESC Heart Failure"
DOI: 10.1002/ehf2.15362
Abstract: Targeting inflammasomes in heart failure (HF) might represent a novel therapeutic option. Nevertheless, previous studies focused only on myocardial inflammasome alterations, and data are scarce regarding their regulation and role in HF‐associated multiorgan dysfunction. Therefore,… read more here.
Keywords: heart; rat model; expression; model advanced ... See more keywords
The capsaicinoid nonivamide suppresses the inflammatory response and attenuates the progression of steatosis in a NAFLD‐rat model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23279
Abstract: Nonalcoholic fatty liver disease (NAFLD) is relatively associated with comorbidities in obesity and metabolic inflammation. Low‐grade inflammation following the high‐fat diet (HFD)‐induced NAFLD can promote the development of nonalcoholic steatohepatitis (NASH) through particularly liver‐resident immune… read more here.
Keywords: pava; rat model; nafld rat;