Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human
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DOI: 10.1080/00498254.2021.1890275
Abstract: Abstract The pharmacokinetics of brexpiprazole were investigated in the in vitro and in vivo. The total body clearance of brexpiprazole in rat and monkey was 2.32 and 0.326 L/h/kg, respectively, after intravenous administration, and oral availability… read more here.
Keywords: metabolism; rat monkey; main metabolite; pharmacokinetics metabolism ... See more keywords