Silk‐in‐Silk Nerve Guidance Conduits Enhance Regeneration in a Rat Sciatic Nerve Injury Model
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202203237
Abstract: Advanced nerve guidance conduits can provide an off‐the‐shelf alternative to autografts for the rehabilitation of segmental peripheral nerve injuries. In this study, the excellent processing ability of silk fibroin and the outstanding cell adhesion quality… read more here.
Keywords: rat sciatic; guidance conduits; silk; nerve ... See more keywords
Multiplex Analysis of the Activation of the Immune System after Transection of the Rat’s Sciatic Nerve
Sign Up to like & getrecommendations! Published in 2017 at "BioNanoScience"
DOI: 10.1007/s12668-016-0332-8
Abstract: In this study, using the model of sciatic nerve transection in rats, the cytokine profile of peripheral blood serum and rat sciatic nerve fragments was measured 3, 7 and 14 days after the injury. Histological analysis… read more here.
Keywords: rat sciatic; analysis; transection; cytokine profile ... See more keywords
Entrapping bupivacaine-loaded emulsions in a crosslinked-hydrogel increases anesthetic effect and duration in a rat sciatic nerve block model.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119703
Abstract: The purpose of this research was to evaluate a novel long-acting bupivacaine delivery system for control of postoperative pain. Bupivacaine-loaded lipid emulsion (BLE) droplets were created by high-speed homogenization. The BLE droplets were then entrapped… read more here.
Keywords: rat sciatic; ble droplets; bupivacaine loaded; bupivacaine ... See more keywords
Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials science"
DOI: 10.1039/c7bm01101f
Abstract: Peripheral nerve injuries (PNI) resulting in a gap to be bridged between the transected nerve ends are commonly reconstructed with autologous nerve tissue, but there is a need for valuable alternatives. This experimental work considers… read more here.
Keywords: rat sciatic; peripheral nerve; nerve; sciatic nerve ... See more keywords
Use of acellular dermal matrix in peripheral nerve reconstruction: an experimental study on rat sciatic nerve defect
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Plastic Surgery and Hand Surgery"
DOI: 10.1080/2000656x.2022.2152824
Abstract: Abstract Background In patients with nerve tissue defects, the use of autologous nerve grafts is the standard method of treatment. Alternatives to autologous, nerve grafts have attracted the attention of reconstructive surgeons. In this study,… read more here.
Keywords: rat sciatic; acellular dermal; group group; nerve ... See more keywords
A modified chemical protocol of decellularization of rat sciatic nerve and its recellularization with mesenchymal differentiated schwann-like cells: morphological and functional assessments.
Sign Up to like & getrecommendations! Published in 2017 at "Histology and histopathology"
DOI: 10.14670/hh-11-844
Abstract: The functional reconstruction of large neural defects usually requires the use of peripheral nerve autografts, though these have certain limitations. As a result, interest in new alternatives for autograft development has risen. The acellular peripheral… read more here.
Keywords: rat sciatic; modified chemical; morphological functional; decellularization ... See more keywords
HFAC Dose Repetition and Accumulation Leads to Progressively Longer Block Carryover Effect in Rat Sciatic Nerve
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.852166
Abstract: This paper describes high-frequency nerve block experiments carried out on rat sciatic nerves to measure the speed of recovery of A fibres from block carryover. Block carryover is the process by which nerve excitability remains… read more here.
Keywords: hfac; rat sciatic; block carryover; nerve ... See more keywords
Assessment of Rat Sciatic Nerve Using Diffusion-Tensor Imaging With Readout-Segmented Echo Planar Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.938674
Abstract: Objectives This study aimed to compare readout-segmented-3, readout-segmented-5, and readout-segmented-7 echo-planar imaging (RS3-EPI, RS5-EPI, and RS7-EPI) of DTI in the assessment of rat sciatic nerve at 3T MR. Methods Eight male adult healthy Sprague-Dawley rats… read more here.
Keywords: rat sciatic; sciatic nerve; readout segmented; epi ... See more keywords
Surgically Induced Demyelination in Rat Sciatic Nerve
Sign Up to like & getrecommendations! Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13050754
Abstract: Demyelination is a common sign of peripheral nerve injuries (PNIs) caused by damage to the myelin sheath surrounding axons in the sciatic nerve. There are not many methods to induce demyelination in the peripheral nervous… read more here.
Keywords: nerve; sciatic nerve; rat sciatic; demyelination rat ... See more keywords
Comparison of Decellularization Protocols to Generate Peripheral Nerve Grafts: A Study on Rat Sciatic Nerves
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22052389
Abstract: In critical nerve gap repair, decellularized nerve allografts are considered a promising tissue engineering strategy that can provide superior regeneration results compared to nerve conduits. Decellularized nerves offer a well-conserved extracellular matrix component that has… read more here.
Keywords: decellularization; rat sciatic; decellularization protocols; sciatic nerves ... See more keywords