Titin-mediated thick filament activation, through a mechanosensing mechanism, introduces sarcomere-length dependencies in mathematical models of rat trabecula and whole ventricle
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DOI: 10.1038/s41598-017-05999-2
Abstract: Recent experimental evidence in skeletal muscle demonstrated the existence of a thick-filament mechanosensing mechanism, acting as a second regulatory system for muscle contraction, in addition to calcium-mediated thin filament regulation. These two systems cooperate to… read more here.
Keywords: rat trabecula; muscle; thick filament; mechanosensing mechanism ... See more keywords