Lentiviral transduction of neonatal rat ventricular myocytes preserves ultrastructural features of genetically modified cells.
Sign Up to like & getrecommendations! Published in 2021 at "Virology"
DOI: 10.1016/j.virol.2021.07.015
Abstract: Preserving morphological features that are important for cell function and structure is a critical parameter for in vitro experiments with rat cardiomyocytes. Lentiviral vectors are commonly used as gene transfer tool because of its high… read more here.
Keywords: features genetically; rat ventricular; ventricular myocytes; neonatal rat ... See more keywords
Myeloperoxidase causes both arrhythmogenic structural and electrical remodelling in neonatal rat ventricular myocyte monolayers
Sign Up to like & getrecommendations! Published in 2023 at "Europace"
DOI: 10.1093/europace/euad122.016
Abstract: Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): This study was supported by Netherlands Organization for Health Research and Development Background Myeloperoxidase (MPO), an enzyme most abundantly… read more here.
Keywords: ventricular myocyte; neonatal rat; control; mpo incubated ... See more keywords
The role of activation of two different sGC binding sites by NO‐dependent and NO‐independent mechanisms in the regulation of SACs in rat ventricular cardiomyocytes
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DOI: 10.14814/phy2.15246
Abstract: The mechanoelectrical feedback (MEF) mechanism in the heart that plays a significant role in the occurrence of arrhythmias, involves cation flux through cation nonselective stretch‐activated channels (SACs). It is well known that nitric oxide (NO)… read more here.
Keywords: ventricular cardiomyocytes; dependent independent; cell; regulation ... See more keywords
Length-Dependent Activation of Contractility and Ca-Transient Kinetics in Auxotonically Contracting Isolated Rat Ventricular Cardiomyocytes
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DOI: 10.3389/fphys.2019.01473
Abstract: Length-dependent activation (LDA) of contraction is an important mechanism of proper myocardial function that is often blunted in diseases accompanied by deficient contractility and impaired calcium homeostasis. We evaluated how the extent of LDA is… read more here.
Keywords: rat ventricular; length dependent; calcium; transient ... See more keywords