DNA damage rather than type I IFN signaling is the primary mediator of neural dysfunction in Aicardi-Goutières syndrome after RNASEH2 disruption
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DOI: 10.1016/j.neuron.2021.11.019
Abstract: Mutations in genes that function in nucleic metabolism have been shown to be linked to Aicardi-Goutières syndrome. In this issue of Neuron, Aditi et al. (2021) provide evidence that DNA damage-dependent signaling rather than type I… read more here.
Keywords: rather type; res syndrome; gouti res; aicardi gouti ... See more keywords