Quantitation of phenylbutyrate metabolites by UPLC-MS/MS demonstrates inverse correlation of phenylacetate:phenylacetylglutamine ratio with plasma glutamine levels.
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DOI: 10.1016/j.ymgme.2017.08.011
Abstract: Urea cycle disorders (UCDs) are genetic conditions characterized by nitrogen accumulation in the form of ammonia and caused by defects in the enzymes required to convert ammonia to urea for excretion. UCDs include a spectrum… read more here.
Keywords: ratio; correlation; phenylbutyrate; plasma glutamine ... See more keywords