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Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer’s disease

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Published in 2023 at "PLOS Genetics"

DOI: 10.1371/journal.pgen.1010681

Abstract: Neurofibrillary lesions composed of tau protein aggregates are defining hallmarks of Alzheimer’s Disease. Despite tau filaments appearing to spread between networked brain regions in a prion-like manner, certain areas including cerebellum resist trans-synaptic spread of… read more here.

Keywords: disease; alzheimer disease; resistance; identification gene ... See more keywords