Lysosomal Adenosine Triphosphate-Activated Upconversion Nanoparticle/Carbon Dot Composite for Ratiometric Imaging of Hepatotoxicity.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03351
Abstract: Drug-induced hepatotoxicity (DIH) is a common cause of acute liver injury, endangering human health. Intracellular adenosine triphosphate (ATP) content in hepatocytes is related to hepatotoxicity. Thus, monitoring the dynamic changes in lysosomal ATP is promising… read more here.
Keywords: activated upconversion; dih; ratiometric imaging; hepatotoxicity ... See more keywords
Protease Activated Probes for Real-Time Ratiometric Imaging of Solid Tumors
Sign Up to like & getrecommendations! Published in 2023 at "ACS Central Science"
DOI: 10.1021/acscentsci.3c00261
Abstract: Surgery is the preferred treatment option for most solid tumors. However, inaccurate detection of cancer borders leads to either incomplete removal of malignant cells or excess excision of healthy tissue. While fluorescent contrast agents and… read more here.
Keywords: ratiometric imaging; real time; solid tumors; tumor ... See more keywords
Label-Free Ratiometric Imaging of Serotonin in Live Cells.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.7b00132
Abstract: Ratiometric imaging can quantitatively measure changes in cellular analyte concentrations using specially designed fluorescent labels. We describe a label-free ratiometric imaging technique for direct detection of changes in intravesicular serotonin concentration in live cells. At… read more here.
Keywords: ratiometric imaging; live cells; label free; free ratiometric ... See more keywords
Ratiometric Imaging of Mitochondrial Hydrogen Peroxide in Aβ42-Mediated Neurotoxicity.
Sign Up to like & getrecommendations! Published in 2022 at "ACS sensors"
DOI: 10.1021/acssensors.1c01381
Abstract: Oxidative stress is important for the etiology and pathogenesis of Alzheimer's disease (AD). Research tools that can conveniently evaluate oxidative stress in AD models are expected to catalyze and accelerate research on AD. This study… read more here.
Keywords: hydrogen peroxide; imaging mitochondrial; ratiometric imaging; oxidative stress ... See more keywords
A method for estimating intracellular ion concentration using optical nanosensors and ratiometric imaging
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11162-8
Abstract: Optical nanoparticle (NP)-based sensors have been widely implemented as tools for detection of targeted ions and biomolecules. The NP sensing platform offer a modular design that can incorporate different sensing components for greater target specificity… read more here.
Keywords: ion concentration; ratiometric imaging; intracellular ion; estimating intracellular ... See more keywords
Nile Red derivatives enable improved ratiometric imaging for nerve-specific contrast
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.23.7.076002
Abstract: Abstract. Surgical nerve damage due to difficulty with identification remains a major risk for postsurgical complications and decreased quality of life. Fluorescence-guided surgery offers a means to specifically highlight tissues of interest such as nerves… read more here.
Keywords: ratiometric imaging; nile red; nerve specific; nerve ... See more keywords
Ratiometric widefield imaging with spectrally balanced detection.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical optics express"
DOI: 10.1364/boe.10.005385
Abstract: Ratiometric imaging is an invaluable tool for quantitative microscopy, allowing for robust detection of FRET, anisotropy, and spectral shifts of nano-scale optical probes in response to local physical and chemical variations such as local pH,… read more here.
Keywords: ratiometric widefield; detection; ratiometric imaging; widefield imaging ... See more keywords
LnNP@ZIF8 Smart System for In Situ NIR-II Ratiometric Imaging-Based Tumor Drug Resistance Evaluation
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12244478
Abstract: Just-in-time evaluation of drug resistance in situ will greatly facilitate the achievement of precision cancer therapy. The rapid elevation of reactive oxygen species (ROS) is the key to chemotherapy. Hence, suppressed ROS production is an… read more here.
Keywords: evaluation; ratiometric imaging; resistance; tumor drug ... See more keywords