Articles with "rational grna" as a keyword



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Rational gRNA design based on transcription factor binding data

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Published in 2021 at "Synthetic Biology"

DOI: 10.1093/synbio/ysab014

Abstract: Abstract The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has become a standard tool in many genome engineering endeavors. The endonuclease-deficient version of Cas9 (dCas9) is also a powerful programmable tool for gene regulation.… read more here.

Keywords: rational grna; transcription factor; factor binding; binding data ... See more keywords