Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non‐treatable Cardiac diseasE (SCIENCE)
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1412
Abstract: Ischaemic heart failure (IHF) patients have a poor prognosis even with current guideline‐derived therapy. Intramyocardial injections of autologous or allogeneic mesenchymal stromal cells might improve cardiac function leading to better clinical outcome. read more here.
Keywords: european multicentre; design european; study stem; multicentre study ... See more keywords
Rationale and design of the HINODE study: Heart failure indication and sudden cardiac death prevention trial Japan
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12577
Abstract: Randomized trials in Western countries have provided evidence that prophylactic implantable cardioverter‐defibrillator (ICD) therapy reduces mortality in heart failure (HF) patients with reduced left ventricular ejection fraction. However, the risk of life‐threatening ventricular arrhythmias in… read more here.
Keywords: heart; heart failure; rationale design; hinode study ... See more keywords
Rationale, design, and methods of a two-site randomized controlled trial: Comparative effectiveness of two treatments for posttraumatic stress disorder in veterans.
Sign Up to like & getrecommendations! Published in 2021 at "Contemporary clinical trials"
DOI: 10.1016/j.cct.2021.106408
Abstract: PTSD is associated with serious problems in interpersonal functioning, including higher rates of marital conflict and divorce, disrupted relationships with family and friends, estrangement from others and social isolation. Cognitive behavioral and trauma focused treatments… read more here.
Keywords: randomized controlled; treatment; rationale design; design methods ... See more keywords
TCT-416 Rationale and design of COMBINE (OCT–FFR) assessment of non-culprit lesions to better predict adverse event outcomes in diabetes mellitus patients.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.09.517
Abstract: Fractional flow reserve (FFR) is a widely used tool for the identification of ischaemia-generating stenoses and to guide decisions on coronary revascularisation. However, the safety of FFR-based decisions in high-risk subsets, such as patients with… read more here.
Keywords: 416 rationale; design combine; combine oct; diabetes mellitus ... See more keywords
Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe)
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DOI: 10.1080/07853890.2022.2132531
Abstract: Abstract Background Limited data are available to establish evidence-based management protocols for vestibulodynia (VBD), a chronic vulvar pain condition that affects approximately 14 million women in the U.S. For the purposes of the study, our… read more here.
Keywords: rationale design; trial; vbd subtypes; efficacy ... See more keywords
Zoster Eye Disease Study: Rationale and Design
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DOI: 10.1097/ico.0000000000002743
Abstract: Purpose: The purpose of this study was to describe the rationale and design of the Zoster Eye Disease Study (ZEDS). Methods: ZEDS is a National Eye Institute–supported randomized clinical trial designed to determine whether 1… read more here.
Keywords: rationale design; disease; eye disease; zoster eye ... See more keywords
Rationale, Design, and Characteristics of the VALIANT (COVID‐19 in Older Adults: A Longitudinal Assessment) Cohort
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DOI: 10.1111/jgs.18146
Abstract: Most older adults hospitalized with COVID‐19 survive their acute illness. The impact of COVID‐19 hospitalization on patient‐centered outcomes, including physical function, cognition, and symptoms, is not well understood. To address this knowledge gap, we collected… read more here.
Keywords: rationale design; older adults; design characteristics; cohort ... See more keywords
The Beijing Desheng Diabetic Eye Study: rationale, design, methodology and baseline data.
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DOI: 10.18240/ijo.2018.01.19
Abstract: AIM To present the rationale, design, methodology, and the baseline data of the Beijing Desheng Diabetic Eye Study (BDDES), and to determine the prevalence of diabetic retinopathy (DR) and possible risk factors in patients with… read more here.
Keywords: methodology; methodology baseline; study; baseline data ... See more keywords