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Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51562
Abstract: The longāterm favorable safety profile of nusinersen provides an opportunity to consider a higher dose. We report on the relationships between nusinersen cerebrospinal fluid (CSF) exposure, biomarker levels, and clinical efficacy.
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Keywords:
neurology;
higher dose;
dose nusinersen;
rationale higher ... See more keywords