Articles with "rationale targeting" as a keyword



Rationale for targeting the Wnt signalling modulator Dickkopf‐1 for oncology

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Published in 2017 at "British Journal of Pharmacology"

DOI: 10.1111/bph.13894

Abstract: Wnt signalling is a fundamental pathway involved in embryonic development and adult tissue homeostasis. Mutations in the pathway frequently lead to developmental defects and cancer. As such, therapeutic intervention of this pathway has generated tremendous… read more here.

Keywords: targeting wnt; rationale targeting; dickkopf; wnt signalling ... See more keywords

A look at duodenal mucosal resurfacing: Rationale for targeting the duodenum in type 2 diabetes

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Published in 2024 at "Diabetes"

DOI: 10.1111/dom.15533

Abstract: Affecting 5%–10% of the world population, type 2 diabetes (T2DM) is firmly established as one of the major health burdens of modern society. People with T2DM require long‐term therapies to reduce blood glucose, an approach… read more here.

Keywords: duodenum; type diabetes; targeting duodenum; duodenal mucosal ... See more keywords