Articles with "rationale targeting" as a keyword



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Rationale for targeting the Wnt signalling modulator Dickkopf‐1 for oncology

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Published in 2017 at "British Journal of Pharmacology"

DOI: 10.1111/bph.13894

Abstract: Wnt signalling is a fundamental pathway involved in embryonic development and adult tissue homeostasis. Mutations in the pathway frequently lead to developmental defects and cancer. As such, therapeutic intervention of this pathway has generated tremendous… read more here.

Keywords: targeting wnt; rationale targeting; dickkopf; wnt signalling ... See more keywords