Rationalizing Promiscuity Cliffs
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DOI: 10.1002/cmdc.201700535
Abstract: Compound promiscuity can be viewed in different ways. We distinguish “bad” promiscuity resulting from chemical liabilities, nonspecific binding, or assay artifacts, from “good” promiscuity representing true multitarget activities. Investigating multitarget activities of small molecules is… read more here.
Keywords: rationalizing promiscuity; multitarget activities; promiscuity; promiscuity cliffs ... See more keywords