Articles with "rationally derived" as a keyword



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Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

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Published in 2020 at "eLife"

DOI: 10.7554/elife.52555

Abstract: Since the 1960s, a single class of agent has been licensed targeting virus-encoded ion channels, or ‘viroporins’, contrasting the success of channel blocking drugs in other areas of medicine. Although resistance arose to these prototypic… read more here.

Keywords: virus hcv; rationally derived; activity; hepatitis virus ... See more keywords