Methotrexate-induced toxic effects and the ameliorating effects of astaxanthin on genitourinary tissues in a female rat model
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-021-06000-2
Abstract: The purpose of the study was to explore the possible deleterious effects of Methotrexate (MTX) treatment on the urogenital tissues and the potential protective effects of Astaxanthin (AXA). Twenty-four female Wistar Albino rats (12 months… read more here.
Keywords: rats received; group rats; compared group; group ... See more keywords
Bone marrow mesenchymal stem cells and condition media diminish inflammatory adhesion molecules of pulmonary endothelial cells in an ovalbumin-induced asthmatic rat model.
Sign Up to like & getrecommendations! Published in 2019 at "Microvascular research"
DOI: 10.1016/j.mvr.2018.10.005
Abstract: OBJECTIVES Although excitements related to stem cell therapeutic outcomes have been highlighted enormously in asthma, the vast majority of works were conducted by researchers in animal models. Elucidating the mechanisms underlying the therapeutic effects of… read more here.
Keywords: icam vcam; rats received; group; model ... See more keywords
Cinnamaldehyde ameliorates STZ-induced diabetes through modulation of autophagic process in adipocyte and hepatic tissues on rats
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-60150-2
Abstract: Type 2 diabetes mellitus is a worldwide public health issue. In the globe, Egypt has the ninth-highest incidence of diabetes. Due to its crucial role in preserving cellular homeostasis, the autophagy process has drawn a… read more here.
Keywords: process; diabetic rats; adipocyte hepatic; cinnamaldehyde ameliorates ... See more keywords
Protective and restorative potency of diosmin natural flavonoid compound against tramadol-induced testicular damage and infertility in male rats
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2090937
Abstract: Abstract Flavonoids are polyphenolic natural compounds with various biological actions and limited toxicity including diosmin (DM) which is considered a safe flavonoid natural type with anti-inflammatory and antioxidant activities. Tramadol (TM) is a centrally long-acting… read more here.
Keywords: protective restorative; testicular damage; tramadol induced; induced testicular ... See more keywords
The ameliorative effects of metformin and taurine against thioacetamide hepatotoxicity in rats.
Sign Up to like & getrecommendations! Published in 2025 at "Toxicology research"
DOI: 10.1093/toxres/tfaf076
Abstract: The main objective of this research was to investigate the therapeutic, anti-inflammatory, and histological effects of metformin and taurine, both alone and in combination, against thioacetamide (TAA)-induced hepatotoxicity in rats. The study included forty adult… read more here.
Keywords: hepatotoxicity rats; effects metformin; group; rats received ... See more keywords
Study of the possible effect of sacubitril/valsartan combination versus valsartan on the cognitive function in Alzheimer’s disease model in rats
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/03946320231161469
Abstract: Objectives: Alzheimer’s disease (AD) is an irreversible, progressive neurodegenerative disorder. The proportion of elderly individuals at risk for AD and cardiovascular problems increases by raising life expectancy. The present study was designed to investigate the… read more here.
Keywords: sacubitril valsartan; model; valsartan; valsartan combination ... See more keywords
Effects of Catha Edulis Forsk on spatial learning, memory and correlation with serum electrolytes in wild-type male white albino rats
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0257932
Abstract: Background The burdens of psychostimulant use disorders are becoming a worldwide problem. One of the psychostimulants widely consumed in Ethiopia and East African countries is Catha edulis Forsk (khat). However, no studies have been conducted… read more here.
Keywords: correlation serum; learning memory; rats received; spatial learning ... See more keywords
Caffeic Acid Alleviates Memory and Hippocampal Neurogenesis Deficits in Aging Rats Induced by D-Galactose
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14102169
Abstract: Hippocampal neurogenesis occurs throughout life, but it declines with age. D-galactose (D-gal) enhances cellular senescence through oxidative stress leading to neurodegeneration and memory impairment. Caffeic acid (CA) acts as an antioxidant via decreasing brain oxidative… read more here.
Keywords: acid alleviates; neurogenesis; hippocampal neurogenesis; memory ... See more keywords